Results 81 to 90 of about 11,869,408 (295)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Escala de percepção da escola como comunidade: evidências de validade fatorial e consistência interna

open access: yesArquivos Brasileiros de Psicologia, 2010
This study aimed at adapting to the Paraibano context the Sense of School as a Caring Community Scale, jointing evidences of its factorial validity and reliability, and to know if its scores are influenced by participants’ sex, scholar degree, and type ...
Patrícia Nunes da Fonseca   +4 more
doaj  

Rocky intertidal macrobenthic communities across a large-scale estuarine gradient

open access: yesScientia Marina, 2010
We evaluated relationships between (1) salinity and species richness and (2) frontal zones and community structure for the rocky intertidal macrobenthic community of the Uruguayan coast.
Luis Giménez   +4 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Association between sarcopenia with lifestyle and family function among community-dwelling Chinese aged 60 years and older

open access: yesBMC Geriatrics, 2017
Background Sarcopenia is defined as the age-related decline in skeletal muscle mass and function. The risk factors and causes of sarcopenia must be identified to develop prevention and treatment strategies for this syndrome.
Shan Hai   +6 more
doaj   +1 more source

A nationwide student survey on biochemistry learning resources in Italy

open access: yesFEBS Open Bio, EarlyView.
We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti   +4 more
wiley   +1 more source

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

open access: yesFEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

Oak Bay Community Green Map: A guide to Oak Bay Treasures

open access: yes, 2012
A map marking sites of cultural, ecological, and historical significance in the District of Oak Bay. Includes two inset maps of the Trial Islands, Chatham, and Discovery Islands. Scale varies on inset maps.
Community Association of Oak Bay
core   +1 more source

Review: The Necessity of Producing/Normalizing Adaptive Behavior Scales in Diagnosing Training Treatment Rehabilitation of Peop e and Assessment of the Programs

open access: yesJournal of Rehabilitation, 2000
Adaptive behavior is defined as the manner in which people cope with the natural and social demands of their environments. Impairments in adaptive behavior are described as significant limitations in an individual's effectiveness in meeting the standards
Seyyed Jalal Sadrosadat   +1 more
doaj  

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

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