Results 71 to 80 of about 5,165,840 (302)

A particle swarm optimization based memetic algorithm for dynamic optimization problems [PDF]

, 2009
Copyright @ Springer Science + Business Media B.V. 2010.Recently, there has been an increasing concern from the evolutionary computation community on dynamic optimization problems since many real-world optimization problems are dynamic.
AS Uyar, B Liu, CK Goh, D Liu, D Parrott, Dingwei Wang, H Ishibuchi, H Wang, H Wang, Hongfeng Wang, J Tang, JE Gallardo, JE Smith, M Tang, N Krasnogor, R Tinos, S Janson, S Man, S Yang, S Yang, S Yang, Shengxiang Yang, TM Blackwell, W. H. Ip, Y Jin, YG Petalas   +25 more
core   +4 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

IMPACT: The Journal of the Center for Interdisciplinary Teaching and Learning. Volume 8, Issue 2, Summer 2019 [PDF]

, 2019
Many of us look for ways to help students forge concrete connections between their academic studies and the real world. Universities encourage professors to develop community-based learning, allowing students to contribute to the community beyond their
Baer, Roberta D., Blair, Janet, Cordner, Sheila, Cruz, Ronald, Flaisher-Grinberg, Shlomit, Girdharry, Kristi, Holbrook, Emily, Iglesias, Charisse S., Knott, Alex, Leard, Cyndy, Oppenheim, Willy, Ramsey, Melanie, Spector, Barbara S., Stone, Debbi   +13 more
core  

Regional surname affinity: a spatial network approach [PDF]

, 2019
OBJECTIVE We investigate surname affinities among areas of modern‐day China, by constructing a spatial network, and making community detection.
Chen, Jiawei, Li, Le, Shi, Yongbin, Stanley, H. Eugene, Wang, Yougui, Yuan, Yida   +5 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

What’s That Frog? Evaluating a Crowdsourced Approach to Species Identification From Audio Recordings

Citizen Science: Theory and Practice
Citizen science is rapidly advancing as a field, engaging the public in scientific research and outcomes, while obtaining large quantities of data.
Grace L. Gillard, Paul K. J. Flemons, Nadiah Roslan, Adam Woods, Jodi J. L. Rowley   +4 more
doaj   +1 more source

The Testbed for LISA Analysis Project

, 2006
The Testbed for LISA Analysis (TLA) Project aims to facilitate the development, validation and comparison of different methods for LISA science data analysis, by the broad LISA Science Community, to meet the special challenges that LISA poses.
Benacquista, Matthew J., Finn, Lee Samuel, Larson, Shane L., Rubbo, Louis J.   +3 more
core  

COCARDE: new view on old mounds – an international network of carbonate mound research [PDF]

, 2012
EGU2012-12550 Carbonate mounds are important contributors of life in different settings, from warm-water to cold-water environments, and throughout geological history.
Dullo, W.C., Foubert, A., Henriet, J.-P., Rüggeberg, A., Spezzaferri, S., The COCARDE Science Community, Van Rooij, D., Vertino, A.   +7 more
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

The “Ants of Cyprus” website: a dynamic, online awareness raising and conservation tool [PDF]

Biodiversity Data Journal
Ants are an important arthropod group due to their involvement in ecological processes amongst others as ecosystem engineers or predators, but some invasive alien species are also implicated in detrimental environmental, economic and human health effects.
Jakovos Demetriou, Christos Georgiadis, Sebastian Salata, Lech Borowiec, Mathias Dillen, Quentin Groom, Evan Economo, Helen Roy, Angeliki Martinou   +8 more
doaj   +3 more sources