Results 71 to 80 of about 32,118,597 (288)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Home gardens contribute to conservation of the critically endangered Wollemi Pine: Evaluation of a botanic garden‐led horticultural release programme

Plants, People, Planet
Societal Impact Statement Botanic gardens play a leading role in conserving plant species worldwide. Wollemi Pine, a critically endangered species described as new to science in 1994, has been the subject of botanic garden‐led conservation efforts ...
Catherine A. Offord, Heidi C. Zimmer
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Science and Community Trusts [PDF]

Science, 1921
n ...
openaire   +3 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

“Everyone wears mitts”: reflections on the use of metaphors in knowledge co-production in Nunavut, Canada

Arctic Science
Co-production has emerged as foundational to meaningful community-based Arctic research, placing Inuit leadership as central to knowledge creation. When founded upon strong relationships, co-production incorporates Indigenisation into research design ...
N.D. Brunet, J.S. Milton, S.-A. Thompson, M. Milton, D.A. Henri, S. Elverum   +5 more
doaj   +1 more source

Extensive sampling and citizen science expand the distribution of the threatened freshwater turtle Ranacephala hogei (Mertens, 1967) [PDF]

Anais da Academia Brasileira de Ciências
Ranacephala hogei is a South American freshwater turtle considered one of the 25 most endangered chelonian species in the world. Endemic to the Atlantic Forest hotspot of southeastern Brazil, the conservation status of R.
CLODOALDO L. ASSIS, RAFAEL M. VALADÃO, SÔNIA HELENA S.T. DE MENDONÇA, EVÓDIO LUIS S. PEÇANHA, HENRIQUE C. COSTA, CAMILA M. NOVAES, THIAGO F. DE BARROS, LAIO S. RODRIGUES, JOÃO LUIZ GASPARINI, RENATO N. FEIO   +9 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

The Vascular Flora of Pisa (Tuscany, Central Italy)

Plants
We present the first vascular flora of the municipality of Pisa. The floristic inventory was built on previous literature and field observations deposited in the online database Wikiplantbase #Toscana, integrated by observations from iNaturalist.
Lorenzo Peruzzi, Brunello Pierini, Iduna Arduini, Gianni Bedini, Jacopo Franzoni   +4 more
doaj   +1 more source