Results 91 to 100 of about 22,400,397 (381)

Microbes as Engines of Ecosystem Function: When Does Community Structure Enhance Predictions of Ecosystem Processes?

Frontiers in Microbiology, 2016
Microorganisms are vital in mediating the earth’s biogeochemical cycles; yet, despite our rapidly increasing ability to explore complex environmental microbial communities, the relationship between microbial community structure and ecosystem processes ...
E. Graham, J. Knelman, A. Schindlbacher, S. Siciliano, M. Breulmann, A. Yannarell, J. Beman, Guy C. J. Abell, L. Philippot, J. Prosser, A. Foulquier, J. Yuste, H. Glanville, Davey L. Jones, Roey Angel, J. Salminen, Ryan J. Newton, H. Bürgmann, L. Ingram, U. Hamer, H. Siljanen, Krista Peltoniemi, K. Potthast, L. Bañeras, M. Hartmann, Samir K. Banerjee, R. Yu, G. Nogaro, Andreas Richter, M. Koranda, S. Castle, M. Goberna, B. Song, A. Chatterjee, O. Nunes, A. Lopes, Yiping Cao, Aurore Kaisermann, S. Hallin, M. Strickland, Jordi Garcia‐Pausas, Josep Barba, Hojeong Kang, K. Isobe, S. Papaspyrou, R. Pastorelli, A. Lagomarsino, E. Lindström, N. Basiliko, D. Nemergut   +49 more
semanticscholar   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Community Structure and Media Risk Coverage [PDF]

, 1994
Professor Dunwoody regards media organizations to be community creatures; their accounts to be social constructions; and answers to, Who\u27s right?
Dunwoody, Sharon
core   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Fertilization Shapes Bacterial Community Structure by Alteration of Soil pH

Frontiers in Microbiology, 2017
Application of chemical fertilizer or manure can affect soil microorganisms directly by supplying nutrients and indirectly by altering soil pH. However, it remains uncertain which effect mostly shapes microbial community structure.
Yuting Zhang, Hong Shen, Xinhua He, B. Thomas, N. Lupwayi, X. Hao, Matthew C. Thomas, Xiaojun Shi   +7 more
semanticscholar   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

FHYSIOGRAPHIC INFLUENCE IN THE STRUCTURE OF THE SUPRABENTHIC FISH ASSEMBLAGE IN THE ROCKY SHORE OF ARRAIAL DO CABO, RIO DE JANEIRO, BRAZIL

Boletim do Instituto de Pesca, 2019
During the summer of 1991, the composition and distribution of the fish assemblage of rocky shore of Arraial do Cabo (RJ), Brazil, was studied using the visual census by area method in five sampling stations.
Marcelo VIANNA
doaj