Results 41 to 50 of about 728,928 (297)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Impact of Community Structure on Cascades [PDF]

Proceedings of the 2016 ACM Conference on Economics and Computation, 2016
We study cascades under the threshold model on sparse random graphs with community structure. In this model, individuals adopt the new behavior based on how many neighbors have already chosen it. Specifically, we consider the permanent adoption model wherein individuals that have adopted the new behavior (or opinion) cannot change their state.
Moharrami, Mehrdad, Subramanian, Vijay, Liu, Mingyan, Lelarge, Marc   +3 more
openaire   +4 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Community public health safety emergency management and nursing insurance service optimization for digital healthy urban environment construction

Frontiers in Public Health, 2022
The purpose of this paper is to promote the construction of digital healthy cities and improve the living standards of urban residents. Based on this, this paper analyzes the development of healthy cities, and studies community public health safety ...
Guosheng Hu, Guosheng Hu, Zeyu Wang, Shaoxiang Jiang, Yuan Tian, Yue Deng, Yue Deng, Yang Liu, Yang Liu   +8 more
doaj   +1 more source

Communication Structure of Cortical Networks [PDF]

Frontiers in Computational Neuroscience, 2011
Large-scale cortical networks exhibit characteristic topological properties that shape communication between brain regions and global cortical dynamics. Analysis of complex networks allows the description of connectedness, distance, clustering, and centrality that reveal different aspects of how the network's nodes communicate.
Luciano da Fontoura Costa, João L. B. Batista, Giorgio A. Ascoli   +2 more
openaire   +3 more sources

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source

Benthic macroinvertebrate community in the Sinos river drainage basin, Rio Grande do Sul, Brazil

Brazilian Journal of Biology
Aquatic macroinvertebrate fauna is a relevant component of limnic continental aquatic ecosystems, playing an important role in several processes with relevant biocomplexity.
M. P. Barros, L. M. Gayeski, J. G. Tundisi   +2 more
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Planktonic Tintinnid Community Structure Variations in Different Water Masses of the Arctic Basin

Frontiers in Marine Science, 2022
Information on tintinnid community structure variations in different water masses in the Arctic Basin is scarce. During the summer of 2020, tintinnid diversity and vertical distribution were investigated in the Arctic Ocean.
Chaofeng Wang, Chaofeng Wang, Chaofeng Wang, Xiaoyu Wang, Zhiqiang Xu, Zhiqiang Xu, Qiang Hao, Yuan Zhao, Yuan Zhao, Yuan Zhao, Wuchang Zhang, Wuchang Zhang, Wuchang Zhang, Tian Xiao, Tian Xiao, Tian Xiao   +15 more
doaj   +1 more source