Results 51 to 60 of about 728,928 (297)

Community Structure in Directed Networks [PDF]

Physical Review Letters, 2008
We consider the problem of finding communities or modules in directed networks. The most common approach to this problem in the previous literature has been simply to ignore edge direction and apply methods developed for community discovery in undirected networks, but this approach discards potentially useful information contained in the edge ...
Mark Newman, Elizabeth Leicht
openaire   +3 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Games With Limited Communication Structure [PDF]

SSRN Electronic Journal, 2007
In this paper we consider cooperative transferable utility games with limited communication structure, called graph games. Agents are able to cooperate with each other only if they can communicate directly or indirectly with each other. For the class of acyclic graph games recently the average tree solution has been proposed.
Talman, A.J.J., Yamamoto, Y.
openaire   +4 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Robustness of community structure in networks [PDF]

Physical Review E, 2008
The discovery of community structure is a common challenge in the analysis of network data. Many methods have been proposed for finding community structure, but few have been proposed for determining whether the structure found is statistically significant or whether, conversely, it could have arisen purely as a result of chance.
Mark Newman, Elizaveta Levina, Brian Karrer   +2 more
openaire   +4 more sources

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Completeness of Community Structure in Networks [PDF]

Scientific Reports, 2017
AbstractBy defining a new measure to community structure, exclusive modularity, and based on cavity method of statistical physics, we develop a mathematically principled method to determine the completeness of community structure, which represents whether a partition that is either annotated by experts or given by a community-detection algorithm ...
Jia-Rong Xie, Pan Zhang, Hai-Feng Zhang, Bing-Hong Wang   +3 more
openaire   +4 more sources

Most autophagic cell death studies lack evidence of causality

FEBS Open Bio, EarlyView.
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley   +1 more source

The Structure of Democratic Communications [PDF]

Social Thought and Research, 1985
Democratic Communications offer the practical, everyday solution to the problem of alienation. Alienation is located in those social relations which systematically distort communication rather than in purely religious or intellectual life. Five such distorting relationships are mentioned.
openaire   +2 more sources