Results 51 to 60 of about 6,115,415 (260)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

National Primary Care Policy (2017) and the roles of community health workers [PDF]

open access: yesRevista Brasileira de Enfermagem
Objective: To analyze the new roles of community health workers as outlined in the 2017 National Primary Care Policy (PNAB) from the perspectives of both nurses and community health workers.
Juliana Roza Dias   +6 more
doaj   +1 more source

Workers have a right to file for workers' compensation for COVID-19. Spanish

open access: yes, 2020
Title from PDF caption (viewed on November 17, 2020)."440-5507s-color (COM/11/20)."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Guide for workers recently hurt on the job. Spanish

open access: yes, 2015
A guide to Oregon's workers' compensation benefits, rights, and responsibilities.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Physical rehabilitation delivery by community health workers: Views of the users and caregivers

open access: yesAfrican Journal of Primary Health Care & Family Medicine
Background: Community health workers are crucial in providing health services at the community level. However, in Zambia, there are limited opportunities for formal physical rehabilitation training for community health workers, leading some to provide ...
Miriam Mapulanga, Thembelihle Dlungwane
doaj   +1 more source

Making ward-based outreach teams an effective component of human immunodeficiency virus programmes in South Africa

open access: yesSouthern African Journal of HIV Medicine, 2018
The implementation of ward-based outreach teams (WBOTs), comprised of community health workers (CHWs), is one of the three interventions of the South African National Department of Health’s (NDoH) Primary Health Care (PHC) Re-engineering strategy for ...
Nireshni Naidoo   +7 more
doaj   +1 more source

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