The partial inhibition of hypothalamic IRX3 exacerbates obesityResearch in context
EBioMedicine, 2019 Background: The Iroquois homeobox 3 (Irx3) gene has been identified as a functional long-range target of obesity-associated variants within the fat mass and obesity-associated protein (FTO) gene. It is highly expressed in the hypothalamus, and both whole-
Thiago Matos de Araujo +9 more
doaj +1 more source
Effect of short-term probiotic Enterococcus faecium SF68 dietary supplementation in overweight and obese cats without comorbidities [PDF]
, 2016 Obesity in cats is associated with metabolic abnormalities and increased susceptibility to diseases such as diabetes mellitus. Studies in mouse models and human beings have shown that probiotics can reduce food intake, promote weight loss and improve ...
Fascetti, A J +3 more
core +1 more source
medRxiv, 2020 The pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in several thousand deaths worldwide in just a few months.
B. G. Pinto +8 more
semanticscholar +1 more source
Differences between physicians in the likelihood of referral and acceptance of elderly patients for dialysis-influence of age and comorbidity [PDF]
, 2007 BACKGROUND: Incidence of dialysis in elderly patients in the Netherlands is low compared to other countries. This study aims to assess the impact of patients' age and comorbidity on the likelihood of referral and acceptance of patients for dialysis and ...
De Jong, P.E. +5 more
core +3 more sources
International Journal of Public Health, 2020 Objectives COVID-19 has a varied clinical presentation. Elderly patients with comorbidities are more vulnerable to severe disease. This study identifies specific symptoms and comorbidities predicting severe COVID-19 and intensive care unit (ICU ...
V. Jain, Jin-Min Yuan
semanticscholar +1 more source
Multi-morbidities are Not a Driving Factor for an Increase of COPD-Related 30-Day Readmission Risk [PDF]
, 2020 Background and Objective: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States. COPD is expensive to treat, whereas the quality of care is difficult to evaluate due to the high prevalence of multi ...
Chukmaitov, Askar +3 more
core +1 more source
Tuberculosis and Respiratory Diseases, 2022 This study aimed to describe the prevalence of comorbidities associated with chronic obstructive pulmonary disease (COPD) and their relation with relevant outcomes. A systematic review based on the PRISMA methodology was performed from January 2020 until
Natasha Cordeiro dos Santos +5 more
semanticscholar +1 more source
Tecido adiposo: suas cores e versatilidade
HU Revista, 2020 Introdução: O tecido adiposo e suas células tem sido amplamente estudados devido à sua relação íntima com a obesidade. Objetivo: Identificar aspectos históricos e relevantes sobre o avanço na compreensão da função metabólica do tecido adiposo, sobretudo ...
Helena Fonseca Raposo
doaj +1 more source
Changes in the prevalence, treatment and control of hypertension in Germany? : a clinical-epidemiological study of 50.000 primary care patients [PDF]
, 2012 INTRODUCTION: Medical societies have developed guidelines for the detection, treatment and control of hypertension (HTN). Our analysis assessed the extent to which such guidelines were implemented in Germany in 2003 and 2001. METHODS: Using standardized
Einsle, Franziska +11 more
core +2 more sources
Uncontrolled hypertension among patients with comorbidities in sub-Saharan Africa : protocol for a systematic review and meta-analysis [PDF]
, 2020 Background Uncontrolled hypertension is the most important risk factor and leading cause of cardiovascular diseases. It is predicted that the number of people with hypertension will increase, and a large proportion of this increase will occur in ...
Asiki, Gershim +6 more
core +1 more source