Results 91 to 100 of about 476,841 (315)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

The impact of comorbidity on cancer survival: a review [PDF]

, 2013
Mette Søgaard,1 Reimar Wernich Thomsen,1 Kristine Skovgaard Bossen,2 Henrik Toft Sørensen,1 Mette Nørgaard1 1Department of Clinical Epidemiology, Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark; 2Danish ...
Søgaard M, Bossen KS, Thomsen RW, Sørensen HT, Nørgaard M   +4 more
core  

Predictive Risk Modelling of Hospital Emergency Readmission, and Temporal Comorbidity Index Modelling Using Machine Learning Methods [PDF]

, 2017
This thesis considers applications of machine learning techniques in hospital emergency readmission and comorbidity risk problems, using healthcare administrative data. The aim is to introduce generic and robust solution approaches that can be applied to
Mesgarpour, M.
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Comorbidity of infectious diseases and anxiety disorders in adults and its association with quality of life: a community study [PDF]

, 2014
Infectious diseases and anxiety disorders are common and both are associated with substantial burden to individual, families, and society. A better understanding of their association may be helpful in explicating possible etiological mechanisms related ...
Meyer, Andrea Hans, Goodwin, Renee D., Andrew T. Gloster, Lieb, Roselind, Renee D Goodwin, Cornelia Witthauer, Roselind eLieb, Roselind Lieb, Witthauer, Cornelia, Gloster, Andrew T., Renee D. Goodwin, Cornelia eWitthauer, Andrea Hans Meyer   +12 more
core   +1 more source

Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study

Frontiers in Medicine
ObjectiveTo investigate the association between polycystic ovary syndrome (PCOS) and inflammatory proteins, and to identify and quantify the role of serum metabolites as potential mediators.MethodsUtilizing summary-level data from a genome-wide ...
Ming-Jie Jia, Li Zhou, Xing-Ning Liu, Hui-Lin Li   +3 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Comorbidity: a Modern View on the Problem; Classification (first notice) [PDF]

, 2015
Introduction. Researches of the famous scientists proved, that comorbid diseases often worsen the course of the underlying disease and/or lead to its chronicity, cause disability and premature death of the working population, often make inefficient ...
Abrahamovych U., Abrahamovych O., Fayura O.   +2 more
core   +1 more source

Recovery From Comorbidity

SAGE Open, 2013
Comorbidity among mood, anxiety, and alcohol disorders is common and burdensome, affecting individuals, families, and public health. A systematic and integrative review of the literature across disciplines and research methodologies was performed ...
Mathew Carter, Colleen Fisher, Mohan Isaac   +2 more
doaj   +1 more source

Comorbidity in cirrhosis

World Journal of Gastroenterology, 2014
Cirrhosis patients' comorbidities are their other diseases than cirrhosis. Comorbidities are neither causes nor consequences of cirrhosis, but they can increase mortality and are therefore clinically important. They are also an important source of confounding in epidemiologic studies.
openaire   +2 more sources