Results 131 to 140 of about 388,394 (322)

Bayesian nonparametric comorbidity analysis of psychiatric disorders [PDF]

arXiv, 2014
The analysis of comorbidity is an open and complex research field in the branch of psychiatry, where clinical experience and several studies suggest that the relation among the psychiatric disorders may have etiological and treatment implications. In this paper, we are interested in applying latent feature modeling to find the latent structure behind ...
arxiv  

Glutamic Acid Decarboxylase Antibodies in Screening for Autoimmune Diabetes: Influence of Comorbidity, Age, and Sex on Specificity and Threshold Values [PDF]

, 1999
Manou R. Batstra, Arianne van Driel, Jacob Petersen, Cees A. van Donselaar, Maarten J. van Tol, G.J. Bruining, Diederick E. Grobbee, Thomas Dyrberg, Henk‐Jan Aanstoot   +8 more
openalex   +1 more source

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

Advanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong, Pei Li, Yi Jiang, Zhihan Wang, Shihui Fu, Hebin Che, Meng Liu, Xiaojing Zhao, Chunlei Liu, Chenghui Zhao, Qin Zhong, Chongyou Rao, Siwei Wang, Suyuan Liu, Dayu Hu, Dongjin Wang, Juntao Gao, Kai Guo, Xinwang Liu, En Zhu, Kunlun He   +20 more
wiley   +1 more source

The impact of comorbidity status on knee function 1 year after total knee arthroplasty: a population-based cohort study

Acta Orthopaedica
Background and purpose. Few studies have examined the impact of comorbidity on functional and clinical knee scores after primary total knee arthroplasty (TKA).
Katrine Glintborg Iversen, Rikke Sommer Haaber, Martin Bækgaard Stisen, André Sejr Klenø, Martin Lindberg-Larsen, Alma Becic Pedersen, Inger Mechlenburg   +6 more
doaj   +1 more source

Effect of Bupropion SR on the Quality of Life of Elderly Depressed Patients With Comorbid Medical Disorders [PDF]

, 1999
Molly Fortner, Kristine Brown, Indu M. Varia, Kenneth Gersing, Christopher M. O’Connor, P. Murali Doraiswamy   +5 more
openalex   +1 more source

Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications

Advanced Science, EarlyView.
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang, Xiaofan Zhu, Zhenzhou Huang, Kaidi Ren, Jie Ran, Yang Yang   +5 more
wiley   +1 more source

Comorbid anxiety predicts lower odds of depression improvement during smartphone-delivered psychotherapy [PDF]

arXiv
Comorbid anxiety disorders are common among patients with major depressive disorder (MDD), and numerous studies have identified an association between comorbid anxiety and resistance to pharmacological depression treatment. However, the impact of anxiety on the effectiveness of non-pharmacological interventions for MDD is not as well understood.
arxiv  

Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration

Advanced Science, EarlyView.
The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan, Meiqian Wu, Chaonan Zhu, Hao Yu, Minh Duc Pham, Katharina Bottermann, Yijie Mao, Yue Wang, Mathias Langner, Mirko Peitzsch, Arka Provo Das, Silke Kauferstein, Jonathan Ward, Peter Mirtschink, Andreas Michael Zeiher, Stefanie Dimmeler, Jaya Krishnan   +16 more
wiley   +1 more source

Graph Transformer with Disease Subgraph Positional Encoding for Improved Comorbidity Prediction [PDF]

arXiv
Comorbidity, the co-occurrence of multiple medical conditions in a single patient, profoundly impacts disease management and outcomes. Understanding these complex interconnections is crucial, especially in contexts where comorbidities exacerbate outcomes. Leveraging insights from the human interactome (HI) and advancements in graph-based methodologies,
arxiv  

Do Comorbidities Influence the Treatment of Myocardial Infarction? [PDF]

, 1997
Rod Passman, Stephen E. Kimmel
openalex   +1 more source