Results 181 to 190 of about 416,375 (296)

Transfer Learning and Permutation‐Invariance Improving Predicting Genome‐Wide, Cell‐Specific and Directional Interventions Effects of Complex Systems

Advanced Science, EarlyView.
SETComp, a transfer learning model based on permutation‐invariance, is pre‐trained on single‐compound intervention data and fine‐tuned on complex system (e.g., natural products) data. The model achieves up to 93.86% accuracy on complex system‐cell‐gene association predictions, outperforming the baseline by up to 27.59%.
Boyang Wang, Boyu Pan, Tingyu Zhang, Qingyuan Liu, Shao Li   +4 more
wiley   +1 more source

Major depressive disorder in multiple sclerosis associated with differences in disease modifying therapy and demographics. [PDF]

Front Neurol
Lee NJ, Hui G, Pike CW, Galetta K, Kipp LB, Dunn J, Le S, Folmsbee SS.   +7 more
europepmc   +1 more source

The Prevalence of Comorbid Depression in Adults With Diabetes [PDF]

, 2001
Ryan J. Anderson, Kenneth E. Freedland, Ray E. Clouse, Patrick J. Lustman   +3 more
openalex   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

A Wearable Electrochemical Biosensor for Salivary Detection of Periodontal Inflammation Biomarkers: Molecularly Imprinted Polymer Sensor with Deep Learning Integration

Advanced Science, EarlyView.
A wearable electrochemical biosensor integrated into a smart mouthguard enables the non‐invasive detection of salivary MMP‐8 for early monitoring of periodontal inflammation. Featuring a molecularly imprinted polymer‐based sensing layer, the platform offers high cytokine selectivity and impedance‐driven sensitivity. Combining wireless connectivity with
Sangheon Jeon, Sung Hyun Kim, Gyeonghwa Heo, Hye Jin Heo, Seon Yeong Chae, Young Woo Kwon, Shin‐Kyu Lee, Dong‐Wook Han, Hyun‐Joo Kim, Yun Hak Kim, Suck Won Hong   +10 more
wiley   +1 more source

Editorial: Sexual abuse and women's mental health

Frontiers in Psychology
Sherry H. Stewart, Sherry H. Stewart, Alessandra M. Passarotti   +2 more
doaj   +1 more source

Comorbidity burden in elderly high-grade glioma patients: impact on radiotherapy outcomes. [PDF]

BMC Cancer
Leiss SM, Wiestler B, Hou HX, Schmottermeyer D, Sackerer V, Diehl C, Peeken J, Borm K, Negwer C, Wagner A, Yakushev I, Delbridge C, Mitsdörffer M, Schmidt-Graf F, Meyer B, Combs S, Bernhardt D.   +16 more
europepmc   +1 more source

Learning and memory impairment in cocaine-dependent and comorbid schizophrenic patients

, 2000
Mark R. Serper, Andrea Bergman, Marc L. Copersino, C. James Chou, Danielle Richarme, Robert Cancro   +5 more
openalex   +1 more source

Prevalence, comorbidity, disability and service utilisation [PDF]

, 2001
Gavin Andrews, Scott Henderson, Wayne Hall   +2 more
openalex   +1 more source

An Effective Oral Drug Delivery Route for Pharmacokinetic Complications: Spirulina Lipid Nanotechnology System

Advanced Science, EarlyView.
Spirulina‐nano system facilitates the formation of drug coating on spirulina's surface through electrostatic adsorption. It targets intestinal villi effectively and overcomes the pharmacokinetic complications of IBS‐D. This system successfully carried out the treatment of multiple symptoms, including diarrhea, visceral hypersensitivity, mental symptoms,
Jiahui Ye, Xinyi Wu, Jin Liu, Yongmi Guo, Chong Ji, Zhouyue Wang, Di Yang, Min Zhou   +7 more
wiley   +1 more source