Results 201 to 210 of about 416,375 (296)

Comorbid illness is an important determinant of health-related quality of life in patients with chronic hepatitis C [PDF]

, 2001
Khozema B. Hussain, Robert J. Fontana, Cheryl A. Moyer, Grace L. Su, Naomi Sneed-Pee, Anna S. Lok   +5 more
openalex   +1 more source

Punicalagin Enhances Autophagy Through Sirtuin 1/FoxO3a Axis to Inhibit Intracellular Mycobacterium Abscessus Infection

Advanced Science, EarlyView.
Punicalagin, a pomegranate molecule, helps the body fight Mycobacterium abscessus. It preferentially boosts interstitial macrophages in the lung, stabilizing mitochondria and switching on the autophagy via SIRT1/FoxO3a, which lowers bacterial load without directly killing bacteria.
Kefan Bi, Bihan Xu, Dan Cao, Kaijin Xu, Ying Zhang   +4 more
wiley   +1 more source

A retrospective study of the impact of comorbidity, polypharmacy and demographic factors on patient inclusion and healthcare delivery in phase I oncology trials. [PDF]

BJC Rep
Nemat H, Orr M, Barrow L, Raobaikady B, Matharu S, Scerri L, Banerji U, Costelloe C.   +7 more
europepmc   +1 more source

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, EarlyView.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

Multimorbidity quantification from the perspective of precision management: challenges and strategies. [PDF]

Ann Med
Huang X, Guo X, Gan Y, Xu A, Sun K, Shen H, Niu Z, Zhang Y, Guo Y, Ma Y, Zhang Y, Wei X.   +11 more
europepmc   +1 more source

Charlson-Deyo Index Impact on Overall Survival After Surgery for Sinonasal Squamous Cell Carcinoma. [PDF]

Laryngoscope Investig Otolaryngol
Herz D, Patel AM, Bebawy GS, Saad AM, Mir GS, Filimonov A.   +5 more
europepmc   +1 more source

Logistic Regression and Machine Learning Algorithms for the Risk Prediction of Perioperative Adverse Cardiovascular Events in Elderly Patients

AGING MEDICINE, EarlyView.
This manuscript focused on developing and validating prediction models for PACEs in elderly patients undergoing noncardiac surgery in China, utilizing routine laboratory examination findings. Logistic regression and machine learning algorithms were employed to construct these models.
Xiao Yan Li, Guang You Duan, Lin Li, Yi Yuan Gao, Li Wen Sun, Silin Zhu, Xiyezi Diao, Ning Wang, He Huang   +8 more
wiley   +1 more source

Association of Heart Rate Variability and Acceleration Plethysmography with Systemic Comorbidity Burden in Patients with Glaucoma. [PDF]

Biomedicines
Yoshida Y, Takei H, Ukisu M, Takagi K, Tanito M.   +4 more
europepmc   +1 more source

New Technologies for Blood Glucose Management in Elderly Diabetics: An Interpretation of the Guidelines for the Management of Diabetes Mellitus in the Elderly in China (2024 Edition)

AGING MEDICINE, EarlyView.
This article reviews the latest advances in diabetes management technologies, and expound the technical principles, clinical benefits, and application dilemmas for elderly diabetes patients. ABSTRACT The burden of diabetes in the elderly is becoming increasingly severe due to the aging population.
Qingyun Cai, Peiyi Zhao, Xinda Chen, Shuyi Yu, Lixin Guo, Qi Pan   +5 more
wiley   +1 more source

Inflammatory Cytokine Signatures Are Associated With Disease Burden and Comorbidity of Episodic Migraine and Endometriosis. [PDF]

Neurol Neuroimmunol Neuroinflamm
Albanese M, Ceci V, Carrera G, Selntigia A, Exacoustos C, Tiberi M, Saracini S, Matteocci A, Mercuri NB, Chiurchiù V.   +9 more
europepmc   +1 more source