Results 221 to 230 of about 1,034,220 (415)

FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity

open access: yesAdvanced Science, EarlyView.
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li   +11 more
wiley   +1 more source

Locus Coeruleus Noradrenergic‐Spinal Projections Contribute to Electroacupuncture‐Mediated Antinociception in Postoperative Pain in Mice

open access: yesAdvanced Science, EarlyView.
How locus coeruleus noradrenergic‐spinal projections and subsequent α2A adrenoceptors‐CaMKII signaling cascades contribute to electroacupuncture‐induced antinociception in postoperative pain in mice is described. Abstract Postoperative pain remains a significant challenge in healthcare.
Wen‐Guang Chu   +13 more
wiley   +1 more source

Comorbidity of five chronic health conditions in elderly communityresidents: determinants and impact on mortality [PDF]

open access: bronze, 2000
Gerda G. Fillenbaum   +4 more
openalex   +1 more source

Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang   +9 more
wiley   +1 more source

Collapsing high-end categories of comorbidity may yield misleading results

open access: yesClinical Epidemiology, 2009
Timothy L LashDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, USA; Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkAbstract: Adequate control of comorbidity has long been recognized as a ...
Timothy L Lash
doaj  

Comorbidity of depression and personality disorders

open access: gold, 1999
Larry J. Siever
openalex   +1 more source

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