Results 221 to 230 of about 699,670 (339)

Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes

Advanced Science, EarlyView.
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo, Josephine A. Robertson, Andrea Aparicio, Kirsten Seale, Qingwen Chen, Anne Richmond, Zhaozhen Du, Mahnoor Sulaiman, Shijie C Zheng, Esteban Ballestar, Charlotte AM Cecil, Bastiaan T Heijmans, Steve Horvath, Varun B. Dwaraka, Jessica Lasky‐Su, Ryan Smith, Riccardo E. Marioni, Andrew E Teschendorff   +17 more
wiley   +1 more source

A metric to measure long-term well-being of people living with HIV in Spain. [PDF]

BMC Med
Fuster-RuizdeApodaca MJ, White TM, Prats-Silvestre C, Holgado-Tello FP, Lazarus JV.   +4 more
europepmc   +1 more source

A Network‐Driven Framework for Drug Response Precision Prediction of Acute Myeloid Leukemia

Advanced Science, EarlyView.
A network‐based precision medicine platform, named NetAML is offered for personalized treatment of AML. It combines network analysis and machine learning to develop 87 models predicting drug sensitivity for clinical drugs. NetAML identifies interpretable gene signatures that drive differential drug responses, enabling the prediction of individual ...
Yinyin Wang, Rui Liu, Yinnan Zhang, Xiang Luo, Chengzhuang Yu, Shentong Fang, Ninghua Tan, Jing Tang   +7 more
wiley   +1 more source

Editorial: Sexual abuse and women's mental health

Frontiers in Psychology
Sherry H. Stewart, Sherry H. Stewart, Alessandra M. Passarotti   +2 more
doaj   +1 more source

The Prevalence of Comorbid Depression in Adults With Diabetes [PDF]

, 2001
Ryan J. Anderson, Kenneth E. Freedland, Ray E. Clouse, Patrick J. Lustman   +3 more
openalex   +1 more source

Lenvatinib Plus Paclitaxel as Second‐Line Therapy for Advanced Gastric Cancer Patients: A Dose Escalation Exploratory Study

Advanced Science, EarlyView.
This study determines the maximum tolerated dose of lenvatinib in combination with paclitaxel as second‐line therapy for advanced gastric cancer patients. A dynamic network biomarker panel associated with patient prognosis and response to treatment is established.
Chenfei Zhou, Jinling Jiang, Liting Guo, Wenqi Xi, Junwei Wu, Qu Cai, Jun Ji, Feng Qi, Jun Zhang   +8 more
wiley   +1 more source

Prevalence, comorbidity, disability and service utilisation [PDF]

, 2001
Gavin Andrews, Scott Henderson, Wayne Hall   +2 more
openalex   +1 more source

ALKBH5‐Mediated M6A Demethylation of G3BP1 Attenuates Ferroptosis Via Cytoplasmic Retention of YBX1/p53 in Diabetic Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li, Wei Li, Yan Leng, Heng Xu, Zhongyuan Xia, Yao Wang   +5 more
wiley   +1 more source

The association between physical activity and the prevalence of comorbidity: a cross-sectional survey. [PDF]

Sci Rep
Fu X, Wang C, Wang Y, Gong L, Liu H, Shen Z, Zhu D, Zhang J, Bai J, Ren R, Cui J, Zhen M, Zhang J, Li X, Miao Y.   +14 more
europepmc   +1 more source

Nicotine, alcohol and drug dependence and psychiatric comorbidity [PDF]

, 2001
Michael Farrell, Samantha Howes, Paul Bebbington, Traolach Brugha, Rachel Jenkins, Glyn Lewis, John Marsden, Colin Taylor, Howard Meltzer   +8 more
openalex   +1 more source