Imipramine plus cognitive behavioural therapy (CBT) was more effective than placebo plus CBT in adolescents with comorbid anxiety and depression who refused to attend school [PDF]
John S. March
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FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li+11 more
wiley +1 more source
Case Study: Missed Diagnosis and Mistreatment of Unrecognized Comorbid Graves Disease
Joseph Woolston, Annmarie Caracansi
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Psychiatric Comorbidity in Chronic Epilepsy: Identification, Consequences, and Treatment of Major Depression [PDF]
Bruce P. Hermann+2 more
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How locus coeruleus noradrenergic‐spinal projections and subsequent α2A adrenoceptors‐CaMKII signaling cascades contribute to electroacupuncture‐induced antinociception in postoperative pain in mice is described. Abstract Postoperative pain remains a significant challenge in healthcare.
Wen‐Guang Chu+13 more
wiley +1 more source
Comorbidity of five chronic health conditions in elderly communityresidents: determinants and impact on mortality [PDF]
Gerda G. Fillenbaum+4 more
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Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain
Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang+9 more
wiley +1 more source
Collapsing high-end categories of comorbidity may yield misleading results
Timothy L LashDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, USA; Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkAbstract: Adequate control of comorbidity has long been recognized as a ...
Timothy L Lash
doaj
Nationwide survey of comorbidity, use, and costs of all medications in Finnish diabetic individuals. [PDF]
Antti Reunanen+3 more
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