Results 41 to 50 of about 5,196 (246)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Ideals of compact operators [PDF]

Journal of the Australian Mathematical Society, 2004
AbstractWe give an example of a Banach spaceXsuch thatK(X, X) is not an ideal inK(X, X**). We prove that ifz* is a weak* denting point in the unit ball of Z* and ifXis a closed subspace of a Banach spaceY, then the set of norm-preserving extensionsH B(x* ⊗z*) ⊆(Z*,Y)* of a functionalx* ⊗Z* ∈ (Z⊗X)* is equal to the setH B(x*) ⊗ {z*}.
Eve Oja, Åsvald Lima
openaire   +3 more sources

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

FEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda, Yuki Naruse, Yusaku Suizu, Tomohiro Araki, Yoshikazu Hoshi, Haruhiko Sakuraba, Junji Hayashi, Toshihisa Ohshima   +7 more
wiley   +1 more source

Compact operators [PDF]

Proyecciones (Antofagasta)
We give a characterization in terms of the transpose operator for a continuous linear operator between locally convex spaces to map bounded sets into relatively weakly compact [relatively compact, precompact] sets. Our results give a known characterization for compact operators between Banach spaces.
openaire   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Quantitative Assessment of Upper Limb Ataxia Using a Virtual Reality‐Based Evaluation System

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebellar ataxia impairs coordination and balance, reducing quality of life. Conventional clinical scales, including the Scale for the Assessment and Rating of Ataxia (SARA) and the International Cooperative Ataxia Rating Scale (ICARS), are widely used to assess ataxia but are limited by subjectivity and inter‐rater variability ...
Masayuki Sato, Takayuki Abe, Sho Aoki, Setsuki Tsukagoshi, Yasushi Yuminaka, Yoshio Ikeda   +5 more
wiley   +1 more source

Compactness properties of operators dominated by AM-compact operators [PDF]

Proceedings of the American Mathematical Society, 2007
We study several properties about the problem of domination in the class of positive AM-compact operators, and we obtain some interesting consequences on positive compact operators. Also, we give a sufficient condition under which a Banach lattice is discrete.
Redouane Nouira, Larbi Zraoula, Belmesnaoui Aqzzouz   +2 more
openaire   +2 more sources

Data‐Driven Distributed Safe Control Design for Multi‐Agent Systems

International Journal of Adaptive Control and Signal Processing, EarlyView.
This paper presents a data‐driven control barrier function (CBF) technique for ensuring safe control of multi‐agent systems (MASs) with uncertain linear dynamics. A data‐driven quadratic programming (QP) optimization is first developed for CBF‐based safe control of single‐agent systems using a nonlinear controller. This approach is then extended to the
Marjan Khaledi, Bahare Kiumarsi
wiley   +1 more source

Approximating compact and weakly compact operators [PDF]

Proceedings of the American Mathematical Society, 1961
REMARKS. To place the theorem in context consider all operators as mapping the Banach space X into the Banach space Y and consider the topology a to be that of almost uniform convergence on the unit ball of X utilizing the norm topology on Y. The second theorem gives a similar result for weakly compact operators.
openaire   +1 more source

Static and Dynamic Behavior of Novel Y‐Shaped Sandwich Beams Subjected to Compressive Loadings: Integration of Supervised Learning and Experimentation

Advanced Engineering Materials, EarlyView.
In this study, the mechanical response of Y‐shaped core sandwich beams under compressive loading is investigated, using deep feed‐forward neural networks (DFNNs) for predictive modeling. The DFNN model accurately captures stress–strain behavior, influenced by design parameters and loading rates.
Ali Khalvandi, Saeed Kamarian, Mahdi Bodaghi, Saeed Saber‐Samandari, Jung‐il Song   +4 more
wiley   +1 more source