Results 71 to 80 of about 10,295,364 (381)

Loop Quantum Gravity on Non-Compact Spaces [PDF]

, 2000
We present a general procedure for constructing new Hilbert spaces for loop quantum gravity on non-compact spatial manifolds. Given any fixed background state representing a non-compact spatial geometry, we use the Gel'fand-Naimark-Segal construction to ...
Arnsdorf, Ashtekar, Ashtekar, Ashtekar, Ashtekar, Ashtekar, Ashtekar, Ashtekar, Baez, Baez, Barbero, DePietri, Grot, Haag, Iwasaki, Iwasaki, Kadison, Landsman, Matthias Arnsdorf, Rovelli, Rovelli, Rovelli, Sameer Gupta, Thiemann   +23 more
core   +3 more sources

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Signature-based Tree for Finding Frequent Itemsets

Journal of Communications Software and Systems, 2023
The efficiency of a data mining process depends on the data structure used to find frequent itemsets. Two approaches are possible: use the original transaction dataset or transform it into another more compact structure.
Mohamed El Hadi Benelhadj, Mohamed Mahmoud Deye, Yahya Slimani   +2 more
doaj   +1 more source

Local support theorem for the exponential Radon transform [PDF]

arXiv, 2023
We prove a local support theorem for the exponential Radon transform for functions of exponential decay at infinity. We also show that our decay condition is essentially sharp for the classical Radon transform for hyperbolic type domains as holes, by showing streched exponential counterexamples.
arxiv  

On positive definite distributions with compact support [PDF]

Banach Journal of Mathematical Analysis, 2015
We propose necessary and sufficient conditions for a distribution (generalized function) $f$ of several variables to be positive definite. For this purpose, certain analytic extensions of $f$ to tubular domains in complex space $\mathbb{C}^n$ are studied. The main result is given in terms of completely monotonic functions on convex cones in $\mathbb{R}^
openaire   +3 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Charged reflecting stars supporting charged massive scalar field configurations

European Physical Journal C: Particles and Fields, 2018
The recently published no-hair theorems of Hod, Bhattacharjee, and Sarkar have revealed the intriguing fact that horizonless compact reflecting stars cannot support spatially regular configurations made of scalar, vector and tensor fields. In the present
Shahar Hod
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source