Results 171 to 180 of about 99,554 (305)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
We introduce and study a new type of compactness principle for strong logics that, roughly speaking, infers the consistency of a theory from the consistency of its small fragments in certain outer models of the set-theoretic universe.
Müller, Sandra +2 more
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Combined Chemical-Physical Modification of Coal Gangue Concrete: ITZ Densification and Enhanced Wetting-Drying Resistance. [PDF]
Materials (Basel)Wei F +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
The Interplay of Curvature, Geometry, and Topology Shapes Tissue Organisation in Epithelial Shells. [PDF]
Adv Sci (Weinh)Morato L +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Explainable machine-learning integration of pre-task and preparatory EEG: revealing complementary predictive information for expert action reliability. [PDF]
Front NeurosciZhao Q, Zhou C.
europepmc +1 more source
ON ALMOST COMPACTNESS AND NEAR COMPACTNESS IN L-TOPOLOGICAL SPACES
The present paper studies several compactness and continuity notions based on the quadruple M = (L,≤,⊗,*), where (L,≤), ⊗ and * respectively denote a complete lattice and binary operations on L, satisfying some further axioms, was introduced by Höhle and
SADIK BAYHAN
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source