Results 221 to 230 of about 1,298,838 (362)

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

ABB Theorems: Results and Limitations in Infinite Dimensions. [PDF]

J Optim Theory Appl
Daniilidis A, De Bernardi CA, Miglierina E.   +2 more
europepmc   +1 more source

Semigroups in compact groups [PDF]

, 1956
Fred B. Wright
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Modeling urban land density with Gaussian and inverse S functions by analyzing urban expansion in Zhengzhou City. [PDF]

Sci Rep
Gao H, Qiao X, Yang Y, Liu L, Zhang J, Zhou H, Zheng Q.   +6 more
europepmc   +1 more source

On a Generalized Notion of Compactness. I

, 1957
I. S. Gál
openalex   +1 more source

A proof of the compactness theorem for arithmetical classes [PDF]

, 1952
Helena Rasiowa
openalex   +1 more source

Characterizations of compactness and countable compactness

Proceedings of the Japan Academy, Series A, Mathematical Sciences, 1973
openaire   +4 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Exploring the interaction and driving factors of urban compactness and carbon emission intensity in the Pearl River Delta Urban Agglomeration. [PDF]

Sci Rep
Yu Y, Kumar S, Ye Z.
europepmc   +1 more source