Results 241 to 250 of about 1,298,838 (362)
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Modification mechanism of silver nanoparticles-functionalized MW-CNT and GGBFS and CQDs on the structural properties of geopolymer reinforced-composite beam. [PDF]
Sci RepKırgız MS +9 more
europepmc +1 more source
Characterization of the space of continuous functions over a compact Hausdorff space [PDF]
, 1947 Richard Arens, John L. Kelley
openalex +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Comprehensive Assessment and Freeze-Thaw Durability Prediction of Wet-Sprayed Concrete for Cold-Region Tunnels. [PDF]
Materials (Basel)Wang H +6 more
europepmc +1 more source
Bohr compactifications of a locally compact abelian group II [PDF]
, 1943 Hirotada Anzai, Shizuo Kakutani
openalex +1 more source
ON COMPACTNESS OF MAPPINGS [PDF]
Proceedings of the National Academy of Sciences, 1964 openaire +3 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
On cardinal numbers related with a compact abelian group [PDF]
, 1943 Shizuo Kakutani
openalex +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source