Results 281 to 290 of about 1,125,486 (341)

In Silico Design and Computational Elucidation of Hypothetical Resveratrol-Curcumin Hybrids as Potential Cancer Pathway Modulators. [PDF]

Pharmaceuticals (Basel)
Sazlı N, Karataş D.
europepmc   +1 more source

Compaction and Diagenesis [PDF]

, 2002
openaire   +3 more sources

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Deletion of MMP12 improves energy metabolism and brown adipose tissue function in mice prone to cardiometabolic disease. [PDF]

J Lipid Res
Amor M, Diaz M, Fuerlinger A, Svecla M, Bianco V, Schooltink L, Dobrijević A, Schwarz B, Akhmetshina A, Vujić N, Korbelius M, Hirtl M, Buerger M, Pirchheim A, Rainer S, Schauer S, Beretta G, Goessler W, Kolb D, Hoefler G, Hackl H, Madreiter-Sokolowski C, Abdellatif M, Norata GD, Kratky D.   +24 more
europepmc   +1 more source

Dynamic Behavior and Refrigeration Performance in a Heat Driven Type Compact Metal Hydride Refrigeration System

, 2008
Sangchul Bae, Masataka Kosaka, Masanori Monde, Masafumi Katsuta   +3 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Exploring the interaction and driving factors of urban compactness and carbon emission intensity in the Pearl River Delta Urban Agglomeration. [PDF]

Sci Rep
Yu Y, Kumar S, Ye Z.
europepmc   +1 more source

Compact Photomultiplier-Tube Base

, 2019
Árpád Barna, A. M. Boyarski
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Divergent selection in moisture-responsive root-branching pathways between tropical and temperate maize germplasm. [PDF]

J Integr Plant Biol
Gangurde SS, Wu C, Zhang J, Prasanna BM, Zhang X.   +4 more
europepmc   +1 more source