Results 301 to 310 of about 1,298,838 (362)
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
On Compactness of Products of Toeplitz Operators. [PDF]
Le T, Rodriguez TM, Şahutoğlu S.
europepmc +1 more source
The Completeness of the Irreducible Unitary Representations of a Locally Compact Group
F. I. Mautner
openalex +1 more source
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
The Fundamentals of the NP-Gram Method for the Characterisation of Pyrolysis Oils Based on the Estimated Boiling Points of Pyrolysis Products from Polypropylene. [PDF]
Brebu M, Murata K.
europepmc +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
Integration of Nuclear, Clinical, and Genetic Features for Lung Cancer Subtype Classification and Survival Prediction Based on Machine- and Deep-Learning Models. [PDF]
Xie B, Mo M, Cui H, Dong Y, Yin H, Lu Z.
europepmc +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Unveiling the morphologies and mechanisms of construction land expansion in border areas of Mainland Southeast Asia. [PDF]
Wang P, Zhang L, Lu R.
europepmc +1 more source