Results 321 to 330 of about 1,317,799 (362)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Global Solutions of the One-Dimensional Compressible Euler Equations with Nonlocal Interactions via the Inviscid Limit. [PDF]

Arch Ration Mech Anal
Carrillo JA, Chen GG, Yuan D, Zatorska E.   +3 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Structure-based molecular screening and dynamic simulation of phytocompounds targeting VEGFR-2: a novel therapeutic approach for papillary thyroid carcinoma. [PDF]

Front Pharmacol
Wang S, Zhang L, Zhang W, Zeng X, Mei J, Xiao W, Yang L.   +6 more
europepmc   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Reconstruction of Indigenous settlements in ecologically fragile areas through spatial distribution patterns and suitability in Xiaoliangshan, SW China. [PDF]

Sci Rep
Addi YW, Li M, Chen X, Yao L, Zhu L, Liu Y, Liao H.   +6 more
europepmc   +1 more source

Structural Modelling of Krüppel-Like Factor 15 Zinc Finger Binding Domain to DNA Using AlphaFold 3.0: Potential Therapeutic Target for Type 2 Diabetes. [PDF]

J Cell Mol Med
Mohammad A, Abubaker J, Marafie SK, AlShawaf E, Ali H, Al-Mulla F.   +5 more
europepmc   +1 more source

Exploring the dynamics of a single vesicle induced by Fe₃O₄ nanoparticles using micropipette manipulation. [PDF]

PLoS One
Ahmed N, Nasrin T, Sayem Karal MA.
europepmc   +1 more source

Development and Characterization of Chitosan Microparticles via Ionic Gelation for Drug Delivery. [PDF]

Polymers (Basel)
Rajabimashhadi Z, Masi A, Bagheri S, Mele C, Colangelo G, Paladini F, Pollini M.   +6 more
europepmc   +1 more source

Differentiation of early-stage tumors from benign lesions manifesting as pure ground-glass nodule: a clinical prediction study based on AI-derived quantitative parameters. [PDF]

Front Oncol
Chen S, Zhang H, Chen Y, Chen S, Cao W, Tong Y.   +5 more
europepmc   +1 more source