First study on the effect of transforming growth factor beta 1 and insulin-like growth factor 1 on the chondrogenesis of elephant articular chondrocytes in a scaffold-based 3D culture model [PDF]
Background and Aim: Osteoarthritis (OA) is recognized as a degenerative joint disease that leads to chronic pain and low quality of life in animals. Captive elephants, the largest land mammals with a long lifespan, are more prone to develop OA due to ...
Siriwan Tangyuenyong +3 more
doaj +1 more source
Exploring animal models in oral cancer research and clinical intervention: A critical review
Cancer is a leading cause of death worldwide, but advances in treatment, early detection, and prevention have helped to reduce its impact. To translate cancer research findings into clinical interventions for patients, appropriate animal experimental ...
Danial Khayatan +2 more
doaj +1 more source
Pumpkin phloem lectin genes are specifically expressed in companion cells. [PDF]
Pumpkin phloem exudate contains two abundant phloem proteins: PP1 is a 96-kD protein that forms polymeric filaments in vivo, and PP2 is a 48-kD dimeric lectin. Polyclonal antibodies raised against pumpkin phloem exudate were used to isolate several cDNAs corresponding to PP1 and PP2.
D E, Bostwick +5 more
openaire +2 more sources
The sieve-element endoplasmic reticulum: A focal point of phytoplasma-host plant interaction?
The rough endoplasmic reticulum (r-ER) is of paramount importance for adaptive responses to biotic stresses due to an increased demand for de novo synthesis of immunity-related proteins and signaling components.
Rita Musetti +6 more
doaj +1 more source
Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals [PDF]
Despite the important progress obtained in the treatment of some pets’ malignancies, new treatments need to be developed. Being critical in cancer control and progression, the immune system’s appropriate modulation may provide effective therapeutic ...
Finocchiaro, Liliana Maria Elena +1 more
core +4 more sources
Epithelial–mesenchymal plasticity and circulating tumor cells: Travel companions to metastases [PDF]
Epithelial–mesenchymal transitions (EMTs) associated with metastatic progression may contribute to the generation of hybrid phenotypes capable of plasticity. This cellular plasticity would provide tumor cells with an increased potential to adapt to the different microenvironments encountered during metastatic spread.
Francart, Marie‐emilie +6 more
openaire +3 more sources
Sieve Elements and Companion Cells—Traffic Control Centers of the Phloem [PDF]
Of all the intricate cell–cell interactions in nature, those between the sieve element (SE) and its companion cell (CC) rank among the most complex and mysterious. Mature SEs are enucleate and retain only a highly degenerate cytoplasm, yet they can remain viable and functional for decades ([
, Oparka, , Turgeon
openaire +2 more sources
Cytopathological evidence for transport of phytoplasma in infected plants
Pleomorphic phytoplasmas were observed in sieve tubes, companion cells and in phloem parenchyma of Tagetes patula L., Helichrysum bracteatum Willd. and Gladiolus sp. L. plants with morphological changes typical for phytoplasma infection.
Anna Rudzińska-Langwald +1 more
doaj +1 more source
Network adaptation improves temporal representation of naturalistic stimuli in drosophila eye: II Mechanisms [PDF]
Retinal networks must adapt constantly to best present the ever changing visual world to the brain. Here we test the hypothesis that adaptation is a result of different mechanisms at several synaptic connections within the network.
A Borst +99 more
core +7 more sources
Solar-Like Cycle in Asymptotic Giant Branch Stars [PDF]
I propose that the mechanism behind the formation of concentric semi-periodic shells found in several planetary nebulae (PNs) and proto-PNs, and around one asymptotic giant branch (AGB) star, is a solar-like magnetic activity cycle in the progenitor AGB ...
Andersen A. C. +6 more
core +3 more sources

