Results 71 to 80 of about 181,456 (272)
Molecules, 2019 Combinations of IL-1β and other proinflammatory cytokines reportedly promote the severity of arthritis. We aimed to investigate the effects of IL-1β combined with IL-17A on cartilage degradation and synthesis in in vitro models.
Patiwat Kongdang +3 more
doaj +1 more source
Span, Cospan, and Other Double Categories [PDF]
, 2012 Given a double category D such that D_0 has pushouts, we characterize oplax/lax adjunctions between D and Cospan(D_0) such that the right adjoint is normal and restricts to the identity on D_0, where Cospan(D_0) denotes the double category on D_0 whose ...
Niefield, Susan
core +1 more source
Gas Giant Protoplanets Formed by Disk Instability in Binary Star Systems
, 2005 We present a suite of three dimensional radiative gravitational hydrodynamics models suggesting that binary stars may be quite capable of forming planetary systems similar to our own.
A. P. Boss +4 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman +17 more
wiley +1 more source
Acta Societatis Botanicorum Poloniae, 2014 In vitro studies of the ontogeny of stomata of young leaves of Tradescantia virginiana L. showed that: 1) translocation of nuclei, often along long, winding paths took place in companion cell mother cells before the onset of asymmetric mitosis, 2) the ...
Jadwiga A. Tarkowska +2 more
doaj +1 more source
Scion on a stock producing siRNAs of potato spindle tuber viroid (PSTVd) attenuates accumulation of the viroid. [PDF]
PLoS ONE, 2013 Plants can attenuate the replication of plant viruses and viroids by RNA silencing induced by virus and viroid infection. In higher plants, silencing signals such as small interfering RNAs (siRNAs) produced by RNA silencing can be transported ...
Atsushi Kasai, Teruo Sano, Takeo Harada
doaj +1 more source
A categorical approach to the maximum theorem [PDF]
, 2017 Berge's maximum theorem gives conditions ensuring the continuity of an optimised function as a parameter changes. In this paper we state and prove the maximum theorem in terms of the theory of monoidal topology and the theory of double categories. This
Koudenburg, Seerp Roald
core +2 more sources
Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy +5 more
wiley +1 more source
Canine pluripotent stem cells: Are they ready for clinical applications?
Frontiers in Veterinary Science, 2015 The derivation of canine embryonic stem cells and generation of canine induced pluripotent stem cells are significant achievements that have unlocked the potential for developing novel cell-based disease models, drug discovery platforms and ...
Dean Harvey Betts +2 more
doaj +1 more source