Results 81 to 90 of about 181,456 (272)

Regulation and Identity of Florigen: Flowering Locus T Moves Center Stage [PDF]

, 2008
The transition from vegetative to reproductive growth is controlled by day length in many plant species. Day length is perceived in leaves and induces a systemic signal, called florigen, that moves through the phloem to the shoot apex.
Borden KL, Bünning E, Chailakhyan M, Fabio Fornara, Franziska Turck, Garner WW, Garner WW, George Coupland, Pnueli L, Ratcliffe OJ, Shin BS, Yoo SY   +11 more
core   +2 more sources

Molecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk, Amanda Cristina Meneguetti Berti, Bárbara Braga Vieira Marques, Victoria Simões Bernardo, Flaviene Felix Torres, Ingrid Souza Dias, Vanessa da Silveira Ramos de Castro, Gabriela Alves Bernardino, Danilo Grünig Humberto da Silva, Edis Belini‐Júnior   +9 more
wiley   +1 more source

Translational immune and metabolic markers of aging in dogs

Scientific Reports
Dogs serve as a promising aging model due to their genetic diversity, condensed lifespan, and shared living environment with humans. Alterations in the immune and metabolic parameters are hallmarks of aging in humans, but few studies have investigated ...
James E. McMahon, Jessica L. Graves, Ashley P. Tovar, Matthew Peloquin, Karen Greenwood, Frances L. Chen, Michelle Nelson, Erin E. McCandless, Celine-Lea Halioua-Haubold, Dina Juarez-Salinas   +9 more
doaj   +1 more source

Global MHD Simulations of Accretion Disks in Cataclysmic Variables (CVs): I. The Importance of Spiral Shocks

, 2016
We present results from the first global 3D MHD simulations of accretion disks in Cataclysmic Variable (CV) systems in order to investigate the relative importance of angular momentum transport via turbulence driven by the magnetorotational instability ...
Ju, Wenhua, Stone, James M., Zhu, Zhaohuan   +2 more
core   +1 more source

Criterion‐Related Validity of the Neuropsychological Quick Assessment for Screening Cognitive, Motor, and Behavioral Impairments in Patients With Pediatric Brain Tumors: An Observational Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neuropsychological complications may impair the qualitative prognosis of patients with pediatric brain tumors. However, multifaceted evaluations cannot be conducted in all patients because they are time consuming and burdensome for patients.
Ami Tabata, Keita Ueda, Tsukasa Ueno, Katsutsugu Umeda, Kentaro Ueno, Kanade Tanaka, Noyuri Nishida, Rie Yamawaki, Megumi Nukui, Yoshiki Arakawa   +9 more
wiley   +1 more source

Helium-ignited violent mergers as a unified model for normal and rapidly declining Type Ia Supernovae

, 2013
The progenitors of Type Ia Supernovae (SNe Ia) are still unknown, despite significant progress during the last years in theory and observations. Violent mergers of two carbon--oxygen (CO) white dwarfs (WDs) are one candidate suggested to be responsible ...
Kromer, M., Pakmor, R., Springel, V., Taubenberger, S.   +3 more
core   +1 more source

Stem Cells and Regenerative Medicine in Domestic and Companion Animals: A Multispecies Perspective [PDF]

Reproduction in Domestic Animals, 2014
ContentsSince their original isolation, the majority of the work on embryonic stem cells (ESC) has been carried out in mice. While the mouse is an outstanding model for basic research, it also has considerable limitations for translational work, especially in the area of regenerative medicine.
N N, Gonçalves, C E, Ambrósio, J A, Piedrahita   +2 more
openaire   +2 more sources

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Mesenchymal stem cells therapy in companion animals: useful for immune-mediated diseases?

BMC Veterinary Research, 2019
Mesenchymal stem cells are multipotent cells, with capacity for self-renewal and differentiation into tissues of mesodermal origin. These cells are possible therapeutic agents for autoimmune disorders, since they present remarkable immunomodulatory ...
Inês Esteves Dias, Pedro Olivério Pinto, Luís Carlos Barros, Carlos Antunes Viegas, Isabel Ribeiro Dias, Pedro Pires Carvalho   +5 more
doaj   +1 more source

Reanalysis of the NCCN PD-L1 companion diagnostic assay study for lung cancer in the context of PD-L1 expression findings in triple-negative breast cancer

Breast Cancer Research, 2019
The companion diagnostic test for checkpoint inhibitor immune therapy is an immunohistochemical test for PD-L1. The test has been shown to be reproducible for expression in tumor cells, but not in immune cells.
David L. Rimm, Gang Han, Janis M. Taube, Eunhee S. Yi, Julia A. Bridge, Douglas B. Flieder, Robert Homer, Anja C. Roden, Fred R. Hirsch, Ignacio I. Wistuba, Lajos Pusztai   +10 more
doaj   +1 more source