Results 41 to 50 of about 26,966 (293)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Happy Traditional and Companionship Marriages [PDF]
, 1988 Happily married couples were interviewed initially and four years later. All the the couples tended to be best friends and very accepting of each other. Results indicated that “companionship” couples worked harder on their marriage than did “traditional”
John Altrocchi
core +1 more source
PLOS Global Public Health, 2023 Women greatly value and benefit from the presence of someone they trust to support them throughout labour and childbirth (‘labour companion of choice’).
Meghan A. Bohren +6 more
doaj +3 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Dogs and the elderly: significant cohabitation and companionship towards the end of life [PDF]
, 2019 We seek comfort from other beings and this often finds a solution in our relationships with dogs. Walter Benjamin said “no single dog is physically or temperamentally like another,” which in part attests to our interspecies domestic closeness based on ...
Bartram, Angela
core
Acta Universitatis Wratislaviensis. Anglica WratislaviensiaThis work considers the reciprocal relationships between people and places, and attempts to explore the possibility of a companionship relationship between human and place.
Wojciech Gałecki
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
PERBEDAAN PERSEPSI COMPANIONSHIP DALAM PERNIKAHAN ANTARA LAKI-LAKI DAN PEREMPUAN [PDF]
, 2020 Indonesian’s divorce rate is the highest among countries in Asia-Pacific, with 70% from total cases were submitted by women. Based on BKKBN data, there are 200 thousands divorce cases each year, and over two millions marriages each year.
Novia, Fifi, Andayani, Budi
core +2 more sources
A Companionship of Fear: Non-Human Companions and the Uses of Terror in the Exeter Book’s Guthlac A
Acta Universitatis Wratislaviensis. Anglica WratislaviensiaThe Exeter Book’s Guthlac A abounds in emotions and tensions manifested in the intensely charged debates between the saint and his demonic assailants.
Rafał Borysławski
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source