Results 51 to 60 of about 2,895,869 (300)
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
ESG disclosure and company profitability: Does company size play a role?
Journal of Enterprise and DevelopmentPurpose — This study aims to examine the relationship between Environmental, Social, and Governance (ESG) disclosures and profitability, with firm size as a moderating variable.
Risal Risal +2 more
doaj +1 more source
Workplace Counselling in Indonesia [PDF]
, 2003 Workplace counselling is aimed at providing support for the physical and mental welfare of employees. This effort will have impact on increasing productivitiy and work performance of employees so that as the end result the company will get a better ...
Mawardi, Artiawati +1 more
core
Systemic risk in the financial sector: what can we learn from option markets? : [version 12 july 2013] [PDF]
, 2013 In this paper, we propose a novel approach on how to estimate systemic risk and identify its key determinants. For all US financial companies with publicly traded equity options, we extract their option-implied value-at-risks (VaRs) and measure the ...
Kraft, Holger, Schmidt, Alexander
core +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
The Effective Factors on Timeliness of Audit Report: Evidence from Iran [PDF]
مطالعات تجربی حسابداری مالی, 2006 An important qualitative attribute of financial statements is timeliness of their information. The recognition that the length of the audit may be the single most important determinant affecting the timeliness of reporting, has motivated recent ...
Farokh Barzideh, Morteza Moayeri
doaj
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Asy Syar'iyyah: Jurnal Ilmu Syariah dan Perbankan Islam, 2018 The objectives of this study included: a) To analyze the effect of profitability on ISR disclosures; b) To analyze the effect of company size on ISR disclosures; c) To analyze the effect of profitability, firm size, on ISR Disclosure simultaneously. The
Marheni Marheni
doaj +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source