Results 181 to 190 of about 556,273 (328)

Development and Comparability of Internalizing and Externalizing Symptom Spectra From Adolescence to Young Adulthood. [PDF]

Int J Methods Psychiatr Res
Birgel V, Rapp M, Tschorn M, Hölling H, Cohrdes C.   +4 more
europepmc   +1 more source

A shortened uncemented stem offers comparable positioning and increased metaphyseal fill compared to a standard uncemented stem [PDF]

, 2019
Alexandre Jacquel, Augustin Le Viguelloux, Jeremy Valluy, Mo Saffarini, Nicolas Bonin   +4 more
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Cord blood buffy coat DNA methylation is comparable to whole cord blood methylation [PDF]

, 2018
John Dou, Rebecca J. Schmidt, Kelly S. Benke, Craig J. Newschaffer, Irva Hertz‐Picciotto, Lisa Croen, Ana‐Maria Iosif, Janine M. LaSalle, M. Daniele Fallin, Kelly M. Bakulski   +9 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Mesenchymal stromal cell-derived extracellular vesicles in regenerative medicine: Standardisation, bioengineering and clinical translation. [PDF]

Regen Ther
Shimizu Y, Inoue Y, Matsuura N, Ishii T, Sowa Y, Sunami H, Ntege EH.   +6 more
europepmc   +1 more source

Elevated core and muscle temperature to levels comparable to exercise do not increase heat shock protein content of skeletal muscle of physically active men [PDF]

, 2007
Yasuharu Oishi
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Clinical Qualification of Subcutaneous Injection Devices for Monoclonal Antibodies. [PDF]

BioDrugs
Bittner B, Munoz J, Frank S, Dolton M, Ravanello R, Dembowski M, Clement A, Richter WF.   +7 more
europepmc   +1 more source

Outcomes for urgent endovascular treatment of non-ruptured symptomatic abdominal aortic aneurysm are comparable to elective repair: a single-centre experience [PDF]

Elena Martín Morales, Javier Río Gómez, Fernando García Boyano, José Manuel Ligero Ramos   +3 more
openalex   +1 more source