Results 101 to 110 of about 1,809,039 (333)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Comparative Advantage and Skill-Specific Unemployment [PDF]
We introduce unemployment and endogenous selection of workers into different skill-classes in a trade model with two sectors and heterogeneous firms. This allows us to study the distributional consequences and the skill-specific unemployment effects of ...
Mario Larch, Wolfgang Lechthaler
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
The Impact of Competitiveness on Economic Growth By Endogenous Growth Model [PDF]
فصلنامه پژوهشهای اقتصادی ایران, 2009 The economic growth rate is an important issue which concerns most of the economic intellectuals, because the economic Growth rate is one of the most important factors which have effect on the human Social welfare.
Jamshid Pazhoyan, Marjan Faghih nasiri
doaj
Labor Markets and Kaleidoscopic Comparative Advantage [PDF]
This paper addresses the labor market implications of an increase in openness and foreign competition. It develops a model where industry-specific productivity shocks create uncertainty, producing an environment of kaleidoscopic comparative advantage ...
Daniel A. Traça
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
LA CONFIGURATION/ LA RECONFIGURATION DE L’IMAGE URBAINE DANS LA CONCURRENCE INTERURBAINE. LE CAS DES VILLES DE BRAȘOV ET DE CONSTANȚA [PDF]
Diversitate si Identitate Culturala in Europa, 2013 In the context of increasingly accentuated globalization, the present cities are forced, in an elegant manner, to act individually in order to ensure economic, social and cultural development.
Teodora Mădălina PAFTALĂ
doaj
Human Services and the Voluntary Sector: Towards a Theory of Comparative Advantage [PDF]
, 1998 David Billis, Howard Glennerster
openalex +1 more source
Adaptive Agent Modeling as a Tool for Trade and Development Theory [PDF]
This paper makes use of an adaptive agent framework to extend traditional models of comparative advantage in international trade, illustrating several cases which make theoretical room for industrial policy and the regulation of trade.
Timothy R. Gulden
core
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source