Results 61 to 70 of about 321,975 (256)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

The Basis for the International Division of Labor and International Trade Is Absolute Rather than Comparative Advantage: Theory and Empirical Evidence

World Review of Political Economy
According to the general consensus in academia, Ricardo’s theory of international trade embodies the theory of comparative advantage. The principle of comparative advantage he proposed, based on the model of physical trade and employing comparative cost ...
Xian Zhang, Jingyuan Fan
doaj   +3 more sources

ANALYSIS OF THE HECKSHER-OHLIN MODEL [PDF]

Annals of Dunarea de Jos University. Fascicle I : Economics and Applied Informatics, 2005
The Hecksher-Ohlin theory is a theory of a long-term general balance where the two factors ofproduction taken into account, namely work and capital, are interchangeable among the fields ofactivity.
Mihaela-Carmen MUNTEAN
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

REVEALED COMPARATIVE ADVANTAGE IN TRADE BETWEEN THE REPUBLIC OF MACEDONIA AND CEFTA 2006

Economic Review, 2018
The aim of this paper is to identify the sectors in which the Republic of Macedonia has a comparative advantage in export to the other member states of CEFTA 2006 (Central European Free Trade Agreement).
Emilija Miteva-Kacarski
doaj   +2 more sources

Competitive and Comparative Advantages Analysis of Organic Rice Farming in Karanganyar Regency, Central Java Province

Ilmu Pertanian (Agricultural Science), 2017
In era of the free trade which increasingly competitive, it is important to understandthe competitiveness of foodstuff commodity by every country. Public awareness of health hazards and adverse environmental impacts, as well as the trend of consumers ...
Anita Suharyati, Slamet Hartono, Lestari Rahayu Waluyati   +2 more
doaj   +1 more source

Research on India-China agriculture trade dynamics: A comparative advantage analysis. [PDF]

PLoS One, 2023
Shukla S, Sadykova K, Tian J.
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Competitiveness analysis of fresh tomatoes in Indonesia: Turning comparative advantage into competitive advantage. [PDF]

PLoS One, 2023
Saptana, Sukmaya SG, Perwita AD, Malihah FD, Wardhana IW, Pitaloka AD, Ghaisani SA, Sayaka B, Ilham N, Karmawati E, Ariani M, Susilowati SH, Sumaryanto, Saliem HP.   +13 more
europepmc   +1 more source