Results 171 to 180 of about 14,378,408 (311)

Equine models in translational medicine: A comparative approach to human health. [PDF]

Animal Model Exp Med
Boozarjomehri Amnieh S, Ropka-Molik K.
europepmc   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Determining parameter impact in systems biology models via sensitivity analysis: a comparative approach. [PDF]

NPJ Syst Biol Appl
Gasior KI.
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

A comparative approach for selecting orthologous candidate genes in genome-wide association studies across multiple species. [PDF]

Plant Physiol
Whitt L, Mahood EH, Ziegler G, Luebbert C, Gillman JD, Norton GJ, Price AH, Salt DE, Dilkes BP, Baxter I.   +9 more
europepmc   +1 more source

In Class With Bertens & Co.: A Very Brief (Comparative, Critical, and Casual) Homage. Forum

, 2011
In Class With Bertens & Co.: A Very Brief (Comparative, Critical, and Casual) Homage ...
RUTHNER, CLEMENS
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Elucidating the genetic architecture of yield components in pyramidale wheat (<i>Triticum turgidum</i> L.): a comparative approach using QTL analysis and genomic selection. [PDF]

Mol Breed
Chen T, Nishimura K, Murata K, Yoshikawa T, Nagasaka K, Maki T, Motoki K, Kinoshita Y, Iwahashi Y, Inoue H, Nakazaki T, Nakano R.   +11 more
europepmc   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Grab Sampling or Passive Samplers? A Comparative Approach to Water Quality Monitoring. [PDF]

Molecules
Cacciatori C, Myers J, Mariani G, Gawlik BM, Pettigrove V.   +4 more
europepmc   +1 more source