Results 101 to 110 of about 369,301 (291)
The Influence of Educational Background on the Self-Identity of Chinese Otome Game Players: A Comparative Study between Higher Education and Non-higher Education Players [PDF]
Z. Li
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Teachers occupy a paradoxical position in contemporary societies: they are central to social reproduction and economic development, yet their profession remains structurally fragile. This article reports on demographic and institutional pressures shaping
Ivan Ivanov +2 more
doaj +1 more source
A Comparative Study of Gastronomy Education in Two Culinary Capitals: Lyon and Gaziantep
Ceyhun UÇUK
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Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
This study comparatively examines the primary school foreign language education curricula and English teacher education systems of Türkiye, Singapore, Norway and the Netherlands, and aims to identify the similarities and differences among these countries’
Osman Özdemir, Zeynep Elmaz
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Comparative education in the era of globalisation: evolution, mission and roles
Mark Bray
openalex +2 more sources

