Results 141 to 150 of about 6,022,305 (300)
Echocardiogram Assessment of Left Ventricular Mass for Hemodialysis Patients
Kidney Medicine, 2020 Dou Huang, Benjamin S. Wessler
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Comparing the Effective Content of Subshifts
Motivated by Ziegler's computability-theoretic characterisation of finite absolute presentability between groups, we prove an analogous theorem in symbolic dynamics. We introduce the notion of one subshift being finitely determined over another and show that this relation is characterised by Ziegler reducibility between their co-languages.
A. Nakid Cordero, I. Scott
openaire +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Comparative effectiveness: its role in the healthcare system.
, 2009 PURPOSE OF REVIEW: To describe comparative effectiveness and assess its role in crafting new healthcare policy. RECENT FINDINGS: Senate Bill S.3408 would establish a nongovernment-affiliated Healthcare Comparative Effectiveness Research Institute that ...
Luo, Betsy P, MD +3 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Medical Devices: Evidence and ResearchHenry C Ssemaganda,1 Sharon E Davis,2 Usha S Govindarajulu,3 Jejo D Koola,4 Jialin Mao,5 Dax Marek Westerman,6 Amy M Perkins,6 Theodore Speroff,7 Craig R Ramsay,8 Art Sedrakyan,5 Lucila Ohno-Machado,9 Michael E Matheny,10,11,* Frederic S Resnic1 ...
Ssemaganda HC +12 more
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