Results 201 to 210 of about 6,022,305 (300)

Comparative Effectiveness of Oral Endotracheal Tube Securement Methods in Adults: A Systematic Review and Network Meta-Analysis. [PDF]

Nurs Rep
Liao CJ, Guo SE, Hsieh MJ, Chao LF.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Comparative Effectiveness of Intravenous, Oral, and Topical Tranexamic Acid in Elective Spine Surgery: A Systematic Review and Network Meta-Analysis. [PDF]

Global Spine J
Hammadeh BM, Sabet CJ, Al-Qunbar A, Sabbah L, Mohammad AK, Hasan Z, Kikhia A, Al-Barbarawi MK.   +7 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Real-world comparative effectiveness of FOLFOX, FOLFIRI, and CapOx as second-line chemotherapy for advanced biliary tract cancer. [PDF]

Oncologist
Chao CY, Tseng KY, Lin HC, Shih YH.
europepmc   +1 more source

Frailty and Early Extubation Independently Influence Postoperative Recovery Following Liver Transplantation—A Retrospective Cohort Study

Journal of Transplantation
Ishan Antony, Noor Albusta, Zhibang Lin, Ryan Nazemian, Bartholomew J. Kane, Ming Valerie Lin   +5 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4-IgG-Positive NMOSD. [PDF]

Ann Clin Transl Neurol
Lin J, Xue B, Xie D, Li J, Pan J, Zhu L, Tong Q, Lin J, Zhu R, Zhang X, Xia J, Li X.   +11 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source