Results 61 to 70 of about 74,016,645 (279)

A Better Way to Generate and Use Comparative-Effectiveness Research [PDF]

, 2009
President Barack Obama, former U.S. Senate majority leader Tom Daschle, and others propose a new government agency that would evaluate the relative effectiveness of medical treatments. The need for "comparative-effectiveness research" is great.
Michael F. Cannon
core   +2 more sources

Single and dual antiplatelet therapy in elderly patients of medically managed myocardial infarction

BMC Geriatrics, 2018
Backgrounds To examine the comparative effectiveness between dual and single antiplatelet therapies in real-world, medically managed elderly patients with acute myocardial infarction (AMI).
Ting-Tse Lin, Hsiu-Yun Lai, K. Arnold Chan, Yen-Yun Yang, Chao-Lun Lai, Mei-Shu Lai   +5 more
doaj   +1 more source

Stakeholder engagement in eight comparative effectiveness trials in African Americans and Latinos with asthma

Research Involvement and Engagement, 2022
Plain English summary The goal of comparative clinical effectiveness research is to compare healthcare options and learn which work best for patients depending on their preferences and circumstances.
Tiffany Dy, Winifred J. Hamilton, C. Bradley Kramer, Andrea Apter, Jerry A. Krishnan, James W. Stout, Stephen J. Teach, Alex Federman, John Elder, Tyra Bryant-Stephens, Rebecca J. Bruhl, Shawni Jackson, Kaharu Sumino   +12 more
doaj   +1 more source

A framework for understanding cancer comparative effectiveness research data needs [PDF]

, 2012
Randomized controlled trials remain the gold standard for evaluating cancer intervention efficacy. Randomized trials are not always feasible, practical, or timely, and often don’t adequately reflect patient heterogeneity and real-world clinical practice.
Kosorok, Michael R., Carpenter, William R., Abernethy, Amy P., Stürmer, Til, Meyer, Anne-Marie   +4 more
core   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Sexual-orientation disparities in whole person health: age- and gender-stratified analysis of patients in a safety-net system

International Journal for Equity in Health
Introduction Despite advancements in LGB+ rights, LGB+ individuals continue to face significant healthcare disparities, particularly in areas such as homelessness, mental health, substance use, health service access, and victimization.
Dhruv Khurana, Maryah Garner, Brittany Bass, Bijan Sasininia, Geoffrey Leung, Anthony Firek   +5 more
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Comparative Effectiveness Research: Challenges for Medical Journals [PDF]

, 2010
Editors from a number of medical journals lay out principles for journals considering publication of Comparative Effectiveness Research (CER). In order to encourage dissemination of this editorial, this article is freely available in PLoS Medicine and ...
Knottnerus, J A, Grimshaw, Jeremy, Tovey, David, Kay Dickersin, Helfand, Mark, Tugwell, Peter, Sox, Harold C, Harold C Sox, Mark Helfand, Sox, Harold C., Knottnerus, J. André, PLoS Medicine Editors, Peter Tugwell, Dickersin, Kay, David Tovey, Jeremy Grimshaw, J André Knottnerus, null null   +17 more
core   +3 more sources

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Effectiveness guidance document (EGD) for acupuncture research - a consensus document for conducting trials

BMC Complementary and Alternative Medicine, 2012
Background There is a need for more Comparative Effectiveness Research (CER) to strengthen the evidence base for clinical and policy decision-making. Effectiveness Guidance Documents (EGD) are targeted to clinical researchers.
Witt Claudia M, Aickin Mikel, Baca Trini, Cherkin Dan, Haan Mary N, Hammerschlag Richard, Hao Jason, Kaplan George A, Lao Lixing, McKay Terri, Pierce Beverly, Riley David, Ritenbaugh Cheryl, Thorpe Kevin, Tunis Sean, Weissberg Jed, Berman Brian M   +16 more
doaj   +1 more source