Results 351 to 360 of about 265,128 (376)

Detection of oncogene amplifications in medulloblastomas by comparative genomic hybridization and array-based comparative genomic hybridization

Journal of Neurosurgery: Pediatrics, 2004
Few studies have been conducted to investigate the genomic survey of oncogene amplification in medulloblastoma. Low frequency of N-myc, C-myc, and epidermal grow factor receptor (EGFR) gene amplification (< 10%) has been reported in medulloblastoma.
Xian Lun Zhu, Angela B.Y. Hui, Ho Keung Ng, Carol Y.K. Tong, Jesse Chung Sean Pang, Wai Sang Poon, Xiao Lu Yin   +6 more
openaire   +3 more sources

Comparative Genomic Hybridization of Wilms’ tumor

2013
Cytogenetic analysis of solid tumors including Wilms' tumor is challenging due to poor chromosome morphology, complexity of abnormalities, and to the possibility of stromal cell overgrowth in tissue culture. Molecular cytogenetic techniques such as chromosomal comparative genomic hybridization (CGH) have improved the diagnosis of chromosomal ...
Evica Rajcan-Separovic, Shahrad Rod Rassekh, Shahrad Rod Rassekh   +2 more
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Comparative genomic hybridization for cytogenetic evaluation of stillbirth

Obstetrics & Gynecology, 2000
To ascertain the feasibility and reliability of comparative genomic hybridization for cytogenetic evaluation of macerated stillbirths.We examined ten stillborn fetuses above 15 weeks' gestation whose karyotypes were unknown because of tissue culture failure. Sixteen fetuses that were successfully karyotyped using prenatal or postnatal tissues were also
P.J Poddighe, J. M. de Pater, J Vissers, G. C. M. L. Christiaens   +3 more
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Comparative genomic hybridization analysis of Wilms tumors

Cytogenetic and Genome Research, 1996
In this study we have applied the technique of comparative genomic hybridization (CGH) to a large series of sporadic Wilms tumors, including six samples of the associated nephroblastomatosis. The data obtained were compared with the findings of molecular studies carried out on the same material.
C. Wiesmeijer, Marcel M.A.M. Mannens, Egbert J.W. Redeker, Marja Steenman, Rosalyn Slater, P.A. Voûte, M. de Meulemeester, Andries Westerveld   +7 more
openaire   +4 more sources

Comparative Genomic Hybridization on Single Cells

2007
Comparative genomic hybridization (CGH) is a molecular cytogenetic technique developed for the analysis of chromosome imbalance in tumors and constitutional chromosome abnormalities. It is based on the analysis of genomic DNA and has the advantage over conventional karyotyping in that it does not require that metaphase chromosomes be obtained from the ...
Lucille Voullaire, Leeanda Wilton
openaire   +3 more sources

Analysis of ameloblastomas by comparative genomic hybridization and fluorescence in situ hybridization

Cancer Genetics and Cytogenetics, 2005
In order to characterize the chromosomal alterations in ameloblastomas, a combination of comparative genomic hybridization (CGH) and fluorescence in situ hybridization (FISH) techniques was performed on 9 tumors. Chromosomal alterations including a gain at 1q and losses at 1pter, 10q, and 22q could be detected by CGH only in 1 tumor.
Toida, M., Balázs, Margit, Rákosy, Zsuzsa, Kató, K., Yamazaki, Y., Matsui, T., Suwa, Tatsuhiko, Hatakeyama, D., Makita, H., Mori, S., Yamashita, Tsuyoshi, Shibata, Toshiyuki, Ádány, Róza, Treszl, Andrea   +13 more
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Comparative Genomic Hybridization for the Analysis of Leukemias and Lymphomas

2003
Cytogenetic methods have become increasingly important tools for both research in hematological malignancies and for the diagnostic workup of leukemias and lymphomas. The knowledge about specific chromosomal aberrations has been an essential prerequisite for the identification of pathogenetically relevant genes. Important examples are molecular genetic
Baudis, Michael, Bentz, Martin
openaire   +4 more sources

High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays

Nature Genetics, 1998
D. Pinkel, R. Segraves, D. Sudar, S. Clark, I. Poole, D. Kowbel, C. Collins, W. Kuo, Chira Chen, Y. Zhai, S. Dairkee, B. Ljung, J. Gray, D. Albertson   +13 more
semanticscholar   +1 more source

The Diagnostic Yield of Array Comparative Genomic Hybridization Is High Regardless of Severity of Intellectual Disability/Developmental Delay in Children

Journal of Child Neurology, 2016
S. D'Arrigo, Francesco Gavazzi, E. Alfei, O. Zuffardi, C. Montomoli, Barbara Corso, E. Buzzi, F. Sciacca, S. Bulgheroni, D. Riva, C. Pantaleoni   +10 more
semanticscholar   +1 more source

Comparative genomic hybridization as a tool in tumour cytogenetics

The Journal of Pathology, 1999
The quality of cytogenetic analysis of solid tumours has greatly improved in the past decade, but a number of technical difficulties remain which limit the characterization of solid tumour chromosomes by conventional cytogenetics alone. The identification of regions of chromosomal abnormality has been aided by the introduction of molecular cytogenetic ...
openaire   +3 more sources