Results 181 to 190 of about 449,093 (327)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Comparative genomics and phylogenetic analysis of seven <i>Ficus</i> species based on chloroplast genomes. [PDF]

PeerJ
Bao S, Deng L, Shi Y, Duan N.
europepmc   +1 more source

Clinical Outcomes of Patients with Colorectal Cancer Who Underwent Comprehensive Genomic Profiling: A Single-institution Non-comparative Prospective Observational Study

Yoshiko Mori, Okihide Suzuki, Noriko Tanabe, Aoi Sugino, Takehiro Shiraishi, Norimichi Chiyonobu, Kenichi Chikatani, Noriyasu Chika, Satoshi Hatano, Takatoshi Matsuyama, Keiichiro Ishibashi, Hideyuki Ishida   +11 more
openalex   +2 more sources

Comparative genomic analysis of Flavobacteriaceae: insights into carbohydrate metabolism, gliding motility and secondary metabolite biosynthesis. [PDF]

, 2020
Asimenia Gavriilidou, Johanna Gutleben, Dennis Versluis, Francesca Forgiarini, Mark WJ van Passel, Colin J. Ingham, Hauke Smidt, Detmer Sipkema   +7 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Comparative genomics of chondrichthyan Hoxa clusters [PDF]

, 2009

core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Comparative Genomics

, 2018
Setubal, João C, Stadler, Peter, Stoye, Jens   +2 more
openaire   +3 more sources

Comparative genomics of <i>Pseudomonas paraeruginosa</i>. [PDF]

J Bacteriol
Déraspe M, Burrows LL, Voulhoux R, Centrón D, Corbeil J, Roy PH.   +5 more
europepmc   +1 more source

Comparative population genomics of crops and their wild relatives [PDF]

, 2010
Chantret, Nathalie, David, Jacques, De Kochko, Alexandre, Glemin, Sylvain, Morcillo, Fabienne, Pham, Jean Louis, Risterucci, Ange-Marie, Ruiz, Manuel, Santoni, Sylvain   +8 more
core