Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight
Cell Reports, 2019 Summary: We found that exposure of adult animals to calorie-dense foods rapidly abolished expression of mitofusin 2 (Mfn2), a gene promoting mitochondrial fusion and mitochondrion-endoplasmic reticulum interactions, in white and brown fat.
Giacomo Mancini +5 more
doaj +1 more source
Comparative Histology and Histochemistry of the Parotid Gland and Mandibular Gland in the Lowland Tapir (Tapirus terrestris Perissodactyla) and Aardvark (Orycteropus afer Tubulidentata). [PDF]
Animals (Basel), 2023 Klećkowska-Nawrot J +4 more
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Ameliorating Effects of Vitamin E on Morphological and Histological Alterations and Oxidative Stress Factors Assessment Against Titanium Dioxide Nanoparticle-Induced in Mice Testis [PDF]
Journal of Advanced Biomedical Sciences, 2020 Background & Objectives: Nano titanium dioxide particles (TiO2) are chemical compounds that are widely used in industrial and foodstuff such as cosmetics, toothpaste, colored materials, and non-fat milk whitening.
ramin jahangirfard +3 more
doaj
Comparative Histology of the Cornea and Palisades of Vogt in the Different Wild Ruminants (Bovidae, Camelidae, Cervidae, Giraffidae, Tragulidae). [PDF]
Animals (Basel), 2022 Klećkowska-Nawrot J +2 more
europepmc +1 more source
Multiple anti-predator mechanisms in the red-spotted Argentina Frog (Amphibia: Hylidae) [PDF]
, 2017 Anurans employ a wide variety of anti-predator mechanisms to defend themselves. In casque-headed hylids, defence is thought to be a complex combination of several anti-predator mechanisms. However, the defence traits of only a few species are known; some
Alcalde, Leandro +6 more
core +2 more sources
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Comparative digital cartilage histology for human and common osteoarthritis models
Orthopedic Research and Reviews, 2013 Douglas R Pedersen, Jessica E Goetz, Gail L Kurriger, James A MartinDepartment of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, USAPurpose: This study addresses the species-specific and site-specific details of weight-bearing ...
Pedersen DR +3 more
doaj
Comparative Histology of C Thyrocytes in Four Domestic Animal Species: Dog, Pig, Horse, and Cattle. [PDF]
Animals (Basel), 2022 Sokołowska J, Cywińska A, Puchalska M.
europepmc +1 more source
Sodium chloride transport of normal and dietary enlarged rat cecum in vitro [PDF]
, 1998 Sodium chloride transport across isolated cecum mucosa was investigated in normal rats and rats with adaptive cecum growth induced by dietary polyethylene glycol (PEG). The normal cecum absorbed CI in excess of Na with a small short-circuit current (Isc).
Loeschke, Klaus +2 more
core +1 more source