Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight
Summary: We found that exposure of adult animals to calorie-dense foods rapidly abolished expression of mitofusin 2 (Mfn2), a gene promoting mitochondrial fusion and mitochondrion-endoplasmic reticulum interactions, in white and brown fat.
Giacomo Mancini +5 more
doaj +1 more source
Voxel-wise comparisons of cellular microstructure and diffusion-MRI in mouse hippocampus using 3D Bridging of Optically-clear histology with Neuroimaging Data (3D-BOND) [PDF]
A key challenge in medical imaging is determining a precise correspondence between image properties and tissue microstructure. This comparison is hindered by disparate scales and resolutions between medical imaging and histology.
Ball, G +6 more
core +6 more sources
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Ameliorating Effects of Vitamin E on Morphological and Histological Alterations and Oxidative Stress Factors Assessment Against Titanium Dioxide Nanoparticle-Induced in Mice Testis [PDF]
Background & Objectives: Nano titanium dioxide particles (TiO2) are chemical compounds that are widely used in industrial and foodstuff such as cosmetics, toothpaste, colored materials, and non-fat milk whitening.
ramin jahangirfard +3 more
doaj
Comparative Histology and Histochemistry of the Parotid Gland and Mandibular Gland in the Lowland Tapir (Tapirus terrestris Perissodactyla) and Aardvark (Orycteropus afer Tubulidentata). [PDF]
Klećkowska-Nawrot J +4 more
europepmc +1 more source
Comparative studies on the histological structure of skin in fresh and brackish water fish
Noura A. Gabr +3 more
openalex +1 more source
Growth, age and size of the Jurassic pachycormid Leedsichthys problematicus (Osteichthyes: Actinopterygii) [PDF]
The Jurassic pachycormid osteichthyan Leedsichthys problematicus is renowned for having been able to achieve prodigious size for a bony fish. Building on work of MARTILL (1986a), a thorough examination of all known material was conducted in order to ...
Adams, C. +3 more
core
Regional diversity in the murine cortical vascular network is revealed by synchrotron X-ray tomography and is amplified with age [PDF]
Cortical bone is permeated by a system of pores, occupied by the blood supply and osteocytes. With ageing, bone mass reduction and disruption of the microstructure are associated with reduced vascular supply.
A Goring +10 more
core +5 more sources
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Comparative digital cartilage histology for human and common osteoarthritis models
Douglas R Pedersen, Jessica E Goetz, Gail L Kurriger, James A MartinDepartment of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, USAPurpose: This study addresses the species-specific and site-specific details of weight-bearing ...
Pedersen DR +3 more
doaj

