Results 101 to 110 of about 209,237 (310)
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Subepithelial connective tissue graft (SCTG) presents favorable outcomes. However, the harvesting technique can influence the anatomical and histological composition of the SCTG.
Ricardo Rabelo Eustachio +7 more
doaj +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Effect of dietary medicinal plant supplementation and aflatoxin B1 contamination on digestive enzymes activity of rainbow trout stocked at various densities [PDF]
The effect of stocking density and dietary aflatoxin B1 along with rosemary and thyme powders on digestive enzymes activity was evaluated in rainbow trout.
Zahra Mahmoudikia +3 more
doaj
The Effect of Eight Weeks of Aerobic Training on MDA, TAC, GPX, and SOD in Heart Tissue of Wistar Rats [PDF]
Introduction and Purpose: Cardiovascular disease is one of the main causes of death in the world. The present study aimed to determine the effect of eight weeks of aerobic exercise on the levels of MDA, TAC, GPX, and SOD in the heart tissue of healthy ...
Elaheh Piralaiy +2 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Detecting breast tissue alterations is essential for cancer diagnosis. However, inherent bidimensionality limits histological procedures’ effectiveness in identifying these changes.
Sandro Donato +9 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source

