Results 51 to 60 of about 2,296,672 (303)

Protective effects of ethyl pyruvate on sperm quality in cyclophosphamide treated mice

Iranian Journal of Reproductive Medicine, 2015
Background: One of the affecting factors in disturbance process of spermatogenesis is chemotherapeutic-induced oxidative stress resulted from cyclophosphamide (CP) treatment which leads to diminished sperm quality via interference in spermatogenesis ...
Zahra Bakhtiary, Rasoul Shahrooz, Abbas Ahmadi, Leila Zarei   +3 more
doaj  

May the palps be with you – new insights into the evolutionary origin of anterior appendages in Terebelliformia (Annelida)

BMC Zoology, 2021
Background Head appendages in Annelida contribute significantly to the immense morphological diversity in this spiralian taxon. Nevertheless, the evolutionary origin of annelid antennae, palps, cirri and tentacles are part of vast theories and debates ...
Paul Kalke, Patrick Beckers, Conrad Helm
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Therapeutic ultrasound and passive mobilisation improve motor function and reduce inflammation in skeletal muscle of immobilised Wistar rats

Journal of Experimental Orthopaedics
Purpose Here we analysed the effects of treatment with therapeutic ultrasound, passive mobilisation and their synergically effects on hind paw' functionality, histomorphometric and immunological aspects in the musculoskeletal tissue in an experimental ...
Fernanda Teixeira Furlan Chico, Ana Caroline Barbosa Retameiro, Aline Reginato, Rafaela Rambo Bremm, Bruna Menegat, Mustafa Munir Mustafa Dahleh, Marina Prigol, Gustavo Petri Guerra, Gladson Ricardo Flor Bertolini, Lucinéia de Fátima Chasko Ribeiro   +9 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Enhancing the learning experience? A comparison of optical and virtual microscope laboratories in Histology and Pathology [PDF]

, 2007
With pressure on universities to teach larger class sizes with fewer resources university teachers are increasingly looking to technology to enhance student learning.
Sudweeks, F., McGill, T.J., Nicholls, P.K., Jonas-Dwyer, D.   +3 more
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The orca (Orcinus orca) pituitary gland: an anatomical, immunohistochemical and ultrastructural analysis

Frontiers in Neuroanatomy
The pituitary gland is central to endocrine regulation in vertebrates, coordinating key physiological processes such as growth, reproduction, and stress responses.
Paula Alonso-Almorox, Paula Alonso-Almorox, Alfonso Blanco, Carla Fiorito, Jose C. Gómez-Villamandos, M. A. Risalde, Javier Almunia, Antonio Fernández   +7 more
doaj   +1 more source

Co-Administration of Vitamin E and Testosterone Attenuates The Atrazine-Induced Toxic Effects on Sperm Quality and Testes in Rats

Cell Journal, 2017
Objective Atrazine (ATZ) as a widely used herbicide is considered as a potent endocrine disrupter which adversely affects reproductive systems in both genders.
Hamed Rezaie Agdam , Mazdak Razi, Amir Amniattalab, Hassan Malekinejad, Morteza Molavi   +4 more
doaj   +1 more source