Results 51 to 60 of about 666,325 (323)

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Fluctuations of the heat flux of a one-dimensional hard particle gas [PDF]

, 2010
Momentum-conserving one-dimensional models are known to exhibit anomalous Fourier's law, with a thermal conductivity varying as a power law of the system size. Here we measure, by numerical simulations, several cumulants of the heat flux of a one-dimensional hard particle gas. We find that the cumulants, like the conductivity, vary as power laws of the
arxiv   +1 more source

Scaling Laws in Jet Classification [PDF]

arXiv, 2023
We demonstrate the emergence of scaling laws in the benchmark top versus QCD jet classification problem in collider physics. Six distinct physically-motivated classifiers exhibit power-law scaling of the binary cross-entropy test loss as a function of training set size, with distinct power law indices. This result highlights the importance of comparing
arxiv  

Energy dependence of the GAFCHROMIC LD‐V1 in the diagnostic radiographic modalities

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract The GAFCHROMIC LD‐V1 radiochromic film is widely used in dosimetry because it can provide high‐resolution two‐dimensional dose distributions without processing. This study aimed to evaluate the response characteristics at different effective energies, from the low‐energy range of mammography to the high‐energy range of computed tomography. Net
Tatsuhiro Gotanda, Tomoyuki Hasuo, Shinnosuke Nishihara, Kohsei Matsuura, Yasuyuki Kawaji, Hidetoshi Yatake, Shinya Imai, Takuya Akagawa, Nobuyoshi Tanki, Toshizo Katsuda   +9 more
wiley   +1 more source

Investment Migration from the Standpoint of International and EU Law [PDF]

The Review of International Affairs
Investment migration programmes are used by over eighty states globally and pose serious security and criminal risks. Their existence is additionally complex in the EU, as EU citizenship opens up its internal market and grants a set of political rights ...
Vesna Ćorić, Fernanda Florentino Fernandez Jankov, Ana Knežević Bojović   +2 more
doaj   +1 more source

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao, Katherine R Schon, Jana Vandrovcova, Özlem Yayıcı Köken, Sharika Raga, Kireshnee Naidu, Maryke Schoonen, Nimita Rani, Pedro Tomaselli, Dipti Baskar, Musambo Kapapa, Ipek Polat, Lindsay A Wilson, Kumarasamy Thangaraj, Uluç Yiş, Bevinahalli N Nandeesh, David Bearden, Michelle Kvalsund, Franclo Henning, Seena Vengalil, Atchayaram Nalini, Claudia F. R. Sobreira, Wilson Marques, Haluk Topoloğlu, Michael G Hanna, Sireesha Yareeda, Venugopalan Y Vishnu, Francois H van der Westhuizen, Izelle Smuts, Surita Meldau, Jo Wilmshurst, Büşranur Çavdarlı, Jeannine Heckmann, Patrick F Chinnery, Rita Horvath   +34 more
wiley   +1 more source

An Opportunity for Reflection – A Special Issue on “The Constitution of Canada: History, Evolution, Influence and Reform”

Perspectives on Federalism, 2017
Canada is and will for the foreseeable future be a peaceful and prosperous liberal democracy whose Constitution Act, 1867, now 150 years old as of 2017, has become a model for the modern world.
Martinico Giuseppe, Albert Richard, Baraggia Antonia, Fasone Cristina   +3 more
doaj   +1 more source

ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib, Kristl G. Claeys, Vera Bril, Yessar Hussain, Kelly Gwathmey, Gregory Sahagian, Elena Cortés‐Vicente, Edward Brauer, Deborah Gelinas, Anne Sumbul, Rosa H. Jimenez, Daniela Hristova, Delphine Masschaele, Renato Mantegazza, Andreas Meisel, Shahram Attarian, On behalf of the ADAPT NXT Study Group   +16 more
wiley   +1 more source

Self-Regulation of genetic studies in Russia: search for the optimal model

RUDN Journal of Law, 2021
The article is devoted to the general analysis of self-regulatory practices of genetic research in Russia (conducted by public research institutions and commercial companies).
Emil V. Alimov, Felix A. Leshchenkov
doaj   +1 more source

First law of black hole mechanics in Einstein-Maxwell and Einstein-Yang-Mills theories [PDF]

Phys.Rev. D68 (2003) 044016, 2003
The first law of black hole mechanics is derived from the Einstein-Maxwell (EM) Lagrangian by comparing two infinitesimally nearby stationary black holes. With similar arguments, the first law of black hole mechanics in Einstein-Yang-Mills (EYM) theory is also derived.
arxiv   +1 more source