Results 51 to 60 of about 263,252 (335)

Convergent and Divergent Connectivity Patterns of the Arcuate Fasciculus in Macaques and Humans

Advanced Science, EarlyView.
This study employs viral‐based single‐neuron tracing and dMRI‐based whole‐brain tractography to investigate arcuate fasciculus (AF) trajectories in macaque monkeys, and compares with the human AF connectome using spectral embedding. Results demonstrate conserved AF topography spanning temporoparietal‐auditory‐frontal pathways across primates, with ...
Jiahao Huang, Ruifeng Li, Wenwen Yu, Anan Li, Xiangning Li, Mingchao Yan, Lei Xie, Qingrun Zeng, Xueyan Jia, Shuxin Wang, Ronghui Ju, Feng Chen, Qingming Luo, Hui Gong, Andrew Zalesky, Xiaoquan Yang, Yuanjing Feng, Zheng Wang   +17 more
wiley   +1 more source

Distinction Between Inflection and Derivation of Learning Reduplication in Mandarin [PDF]

, 2019
Reduplication as a word-formation process in Mandarin, which is one of the most difficult knowledge to comprehend for scholar and student. Theoretically this research offers an approach that is different from what has been made by previous researchers ...
Mastoyo, Y. T. (Y), Sutami, H. (Hermina), Wijana, I. D. (I), Yuxin, S. (Shi)   +3 more
core   +3 more sources

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

OBUSight: Clinically Aligned Generative AI for Ophthalmic Ultrasound Interpretation and Diagnosis

Advanced Science, EarlyView.
OBUSight, a clinically aligned generative AI model that jointly generates reports and predicts diseases through multimodal semantic alignment, was trained and validated on a large multicenter dataset. OBUSight outperformed eight state‐of‐the‐art models, provided clinically reliable reports, enhanced diagnostic efficiency, and achieved performance ...
Xiaocong Liu, An Shao, Bingtao Guan, Ziyao Luo, Weiyi Lai, Xiaoling Huang, Jun Liu, Jie Yan, Huimin Li, Xiangji Pan, Jiawei Wang, Zichang Su, Yih Chung Tham, Jie Yang, Haotian Lin, Juan Ye, Hongxia Xu, Jian Wu   +17 more
wiley   +1 more source

Archibald Henry Sayce (1845–1933) and the Transition from 19th-Century Comparative Philology to 20th-Century General Linguistics

Studia Anglica Posnaniensia, 2023
In language study in the West, the nineteenth century was dominated by comparative philology, and the past century by general linguistics. In the last quarter of the nineteenth century, linguists introduced ideas inconsistent with traditional comparative
Subbiondo Joseph L., Kilarski Marcin
doaj   +1 more source

Modern and Ancient Genomes Reveal Neolithic Paternal Expansions of Millet and Rice Farmers and Demic Diffusion from China into Mainland Southeast Asia

Advanced Science, EarlyView.
This study clarifies the genetic patterns of paternal lineages across East Asia and Mainland Southeast Asia. Han populations are relatively homogeneous, whereas southern ethnolinguistic minorities display regional structures. Shared Y‐chromosome lineages indicate Neolithic expansions and extensive north‐south gene flow, supporting demic diffusion ...
Yunhui Liu, Lintao Luo, Yutong Jiang, Minzhu Zhao, Ting Yang, Zhiyong Wang, Lisiteng Luo, Yuhang Feng, Zihao Zhu, Yuzhu Wang, Limei Zhang, Bofeng Zhu, Chao Liu, Renkuan Tang, Mengge Wang, Guanglin He   +15 more
wiley   +1 more source

General linguistics and Indo-European reconstruction [PDF]

, 2010
There is good reason to be ambivalent about the usefulness of general considerations in linguistic reconstruction. As a heuristic device, a theoretical framework can certainly be helpful, but the negative potential of aprioristic considerations must not ...
Kortlandt, Frederik H. H.
core  

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

The Slovene neo-circumflex revisited

Rasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2012
Keith Langston disagrees with my account of the Slovene neo-circumflex. He rejects compensatory lengthening as an explanation of the neo-circumflex, primarily on theoretical grounds.
Frederik Kortlandt
doaj  

The Linguistic Roots of Religious Studies [PDF]

Вестник Православного Свято-Тихоновского гуманитарного университета: Серия I. Богословие, философия, 2014
The author discusses how linguistics influenced the formation of the methodology and the theory of religious studies. Changes in religious paradigms were connected with the following new theories in linguistics: comparative methodology, structuralism, and
G. Tselkovsky
doaj   +1 more source