Results 41 to 50 of about 856,790 (293)

Comparing Canada, the European Union, and NAFTA: Comparative Capers and Constitutional Conundrums. Jean Monnet/Robert Schuman Paper Series, Vol. 3 No. 4, August 2003 [PDF]

open access: yes, 2003
(From the introduction). This is an exercise in comparative analysis. The paper examines Canada, the European Union, and the North American Free Trade Agreement (NAFTA). Its underlying premise - that political systems are best seen in comparative context
Wolinetz, Steven B.
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The online hostility hypothesis: representations of Muslims in online media

open access: yesSocial Influence, 2023
Using a large data set of online media content in eight European countries, this paper broadens the empirical investigation of the online hostility hypothesis, which posits that interactions on social sites such as blogs and forums contain more hostile ...
Linn Sandberg   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Professor Catherine Boone interview: Land rights and conflict in Africa [PDF]

open access: yes, 2014
Catherine Boone, Professor of Comparative Politics and African Political Economy, was interviewed by The Washington Post about her latest book, Property and Political Order in Africa: Land Rights and the Structure of ...
Boone, Catherine
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Social Networks in Comparative Perspective [PDF]

open access: yes, 2011
In a sense, the study of comparative politics is the study of the role that context plays in structuring behavior. Institutional contexts, such as the nature of the electoral system or the existence of an independent judiciary, drive differences in ...
Siegel, David A
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Improving public support for climate action through multilateralism

open access: yesNature Communications, 2022
A new study reports survey-experimental results suggesting that multilateral approaches to climate action increase domestic carbon tax approval. The appeal of multilateralism reflects improved sustainability beliefs about effectiveness, fairness, and ...
Michael M. Bechtel   +2 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

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