Results 51 to 60 of about 856,790 (293)
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
University Rating in the Global Educational Space
Introduction. In assessing the quality of education, the author applies the rating approach. To date, a set of the most famous and authoritative ratings has been formed.
Ekaterina A. Antyukhova
doaj +1 more source
Comment on 'What To Do (and Not To Do) with Times-Series-Cross-Section Data' [PDF]
Much as we would like to believe that the high citation count for this article is due to the brilliance and clarity of our argument, it is more likely that the count is due to our being in the right place (that is, the right part of the discipline) at
Beck, Nathaniel, Katz, Jonathan N.
core
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Rewards at the top: the European Union [PDF]
Book synopsis: Anyone observing the recent scandals in the United Kingdom could not fail to understand the political importance of the rewards of high public office.
Dimitrakopoulos, Dionyssis G. +1 more
core
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
How Populism and Polarization Affect Europe’s Liberal Democracies
In recent years, two phenomena have put Europe’s liberal democracies under strain: populism and polarization. The rise of populist parties, the increasing radicalization of publics and political discourse, as well as the expansion of hyperpartisan media ...
Heidi Schulze, Marlene Mauk, Jonas Linde
doaj +1 more source
For What it’s Worth: The Political Construction of Quality in French and Italian Wine Markets
At the heart of political organization, we find weak and atomized individuals who aggregate their power to challenge concentrated power. Wine politics show us that within market economies we find the same political movements.
Carter, E.
core +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source

