Results 51 to 60 of about 5,692,557 (359)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Professor Catherine Boone interview: Land rights and conflict in Africa [PDF]

open access: yes, 2014
Catherine Boone, Professor of Comparative Politics and African Political Economy, was interviewed by The Washington Post about her latest book, Property and Political Order in Africa: Land Rights and the Structure of ...
Boone, Catherine
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Improving public support for climate action through multilateralism

open access: yesNature Communications, 2022
A new study reports survey-experimental results suggesting that multilateral approaches to climate action increase domestic carbon tax approval. The appeal of multilateralism reflects improved sustainability beliefs about effectiveness, fairness, and ...
Michael M. Bechtel   +2 more
doaj   +1 more source

Comment on 'What To Do (and Not To Do) with Times-Series-Cross-Section Data' [PDF]

open access: yes, 2006
Much as we would like to believe that the high citation count for this article is due to the brilliance and clarity of our argument, it is more likely that the count is due to our being in the right place (that is, the right part of the discipline) at
Beck, Nathaniel, Katz, Jonathan N.
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Comparing Canada, the European Union, and NAFTA: Comparative Capers and Constitutional Conundrums. Jean Monnet/Robert Schuman Paper Series, Vol. 3 No. 4, August 2003 [PDF]

open access: yes, 2003
(From the introduction). This is an exercise in comparative analysis. The paper examines Canada, the European Union, and the North American Free Trade Agreement (NAFTA). Its underlying premise - that political systems are best seen in comparative context
Wolinetz, Steven B.
core  

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

Social Networks in Comparative Perspective [PDF]

open access: yes, 2011
In a sense, the study of comparative politics is the study of the role that context plays in structuring behavior. Institutional contexts, such as the nature of the electoral system or the existence of an independent judiciary, drive differences in ...
Siegel, David A
core   +2 more sources

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