Results 61 to 70 of about 5,692,557 (359)
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Regulating Uber: The Politics of the Platform Economy in Europe and the United States
Perspectives on Politics, 2018 I use the case of the transportation network company Uber as a lens to explore the comparative politics of the platform economy in Europe and the United States.
K. Thelen
semanticscholar +1 more source
University Rating in the Global Educational Space
Вестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2020 Introduction. In assessing the quality of education, the author applies the rating approach. To date, a set of the most famous and authoritative ratings has been formed.
Ekaterina A. Antyukhova
doaj +1 more source
Rewards at the top: the European Union [PDF]
, 2012 Book synopsis: Anyone observing the recent scandals in the United Kingdom could not fail to understand the political importance of the rewards of high public office.
Dimitrakopoulos, Dionyssis G. +1 more
core
FEBS Open Bio, EarlyView.Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source
How Populism and Polarization Affect Europe’s Liberal Democracies
Politics and Governance, 2020 In recent years, two phenomena have put Europe’s liberal democracies under strain: populism and polarization. The rise of populist parties, the increasing radicalization of publics and political discourse, as well as the expansion of hyperpartisan media ...
Heidi Schulze, Marlene Mauk, Jonas Linde
doaj +1 more source
Complexity, strategic thinking and organisational change [PDF]
, 2003 Comparative considerations of strategy from complexity paradigm and Newtonian paradigm perspectives are discussed in the light of three ideological dispositions towards the future. We term them defensive, opportunist, and goal oriented.
Carlisle, Ysanne, McMillan, Elizabeth
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FEBS Open Bio, EarlyView.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source