Results 121 to 130 of about 5,309,629 (283)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Ordering Things: The Irish State Administration Database [PDF]

open access: yes
New theoretical approaches to the state have posed challenges for the comparative analysis of the organizational features of states. The analysis of state bodies and state agencies has largely been confined to the sub-discipline of public administration,
Colin Scott, Niamh Hardiman
core  

Developments in Labour Law from a Comparative Perspective [PDF]

open access: yes, 2015
The “Labour Law Education Society”, established in 2012, is one of the academic networks which were brought to life to study labour law from a comparative perspective. This monograph is a result of research made by LLES Members.
Florczak, Izabela   +10 more
core  

Extreme Speech| A Comparative Approach to Social Media Extreme Speech: Online Hate Speech as Media Commentary

open access: yesInternational Journal of Communication, 2019
By exploring lessons learned from Ethiopia and Finland, this article challenges two assumptions about online hate speech research. First, it challenges the assumption that the best way to understand controversial concepts such as online hate speech is ...
Matti Pohjonen
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

International gaming: comparative survey research on digital gaming [PDF]

open access: yes, 2011
Computer and console gaming has become a major entertainment sector around the globe. Still, the diffusion rates and the general acceptance of gaming vary between countries.
Chen, Vivian   +7 more
core   +1 more source

Winds of Change? BRICS as a Perspective in International Media Research

open access: yesInternational Journal of Communication, 2018
This article explores the potential that BRICS (Brazil, Russia, India, China, and South Africa) has in providing an alternative angle of analysis to the Western centrism that still dominates the international media studies landscape.
Afonso de Albuquerque   +1 more
doaj  

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