Results 61 to 70 of about 2,595,369 (310)

Learning relationships from theory to design [PDF]

, 1999
This paper attempts to bridge the psychological and anthropological views of situated learning by focusing on the concept of a learning relationship, and by exploiting this concept in our framework for the design of learning technology.
Fowler, C.J.H., Mayes, J.T.
core   +4 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Protective Effects of Albuterol, Epinephrine and Cromolyn Against Ovalbumine-Induced Immunotoxicity in the Rat Lungs [PDF]

Journal of Advanced Biomedical Sciences, 2020
Background & Objective: Asthma is a condition in which the respiratory tract is tight and swollen and is associated with increased levels of mucus and inflammatory cells in the airways.
Raham Armand, Mohhamad kazem koohi, Goodarz Sadeghi Hashtchin, Vahhab Babapour, Nasim khankhajeh   +4 more
doaj  

The Indian Economy Since Liberalisation: the Structure and Composition of Exports and Industrial Transformation (1980 – 2000) [PDF]

, 2004
This paper assesses empirically structural change in the Indian manufacturing based export sector, based on an analysis of 143 industries / product groupings (mainly manufacturing industries).
Dietrich, M., Sharma, A.
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Transcriptomic landscape of Hras12V oncogene-induced hepatocarcinogenesis with gender disparity

BMC Cancer
The genesis of hepatocellular carcinoma (HCC) is closely related to male factors and hyper-activated Ras signals. A transcriptomic database was established via RNA-Seq of HCC (T) and the adjacent precancerous liver tissue (P) of Hras12V transgenic mice ...
Huaiyuan Di, Zhuona Rong, Nan Mao, Huiling Li, Jun Chen, Renwu Liu, Aiguo Wang   +6 more
doaj   +1 more source

Tracking animal movements using biomarkers in tail hairs: a novel approach for animal geolocating from sulfur isoscapes

Movement Ecology, 2020
Background Current animal tracking studies are most often based on the application of external geolocators such as GPS and radio transmitters. While these technologies provide detailed movement data, they are costly to acquire and maintain, which often ...
Zabibu Kabalika, Thomas A. Morrison, Rona A. R. McGill, Linus K. Munishi, Divine Ekwem, Wilson Leonidas Mahene, Alex L. Lobora, Jason Newton, Juan M. Morales, Daniel T. Haydon, Grant G. J. C. Hopcraft   +10 more
doaj   +1 more source

Knowledge-based industry and regional growth [PDF]

, 2005
One of the most important but less understood phenomena in the beginning of the 21st century has been a shift toward knowledge-based economic activity in the comparative advantage of modern industrialized countries.
Park, Sam Ock
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

The Evolution of Comparative Advantage: Measurement and Welfare Implications [PDF]

Using an industry-level dataset of production and trade spanning 75 countries and 5 decades, and a fully speciÞed multi-sector Ricardian model, we estimate productivities at sector level and examine how they evolve over time in both developed and ...
Andrei A. Levchenko, Jing Zhang
core