Results 181 to 190 of about 14,581 (303)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Bone Mineral Density and Serum Levels of Bone Remodeling Markers in Ankylosing Spondylitis Treated with Anti TNF-α Agents. [PDF]

Med Sci (Basel)
Alvarez-Ayala EG, Gamez-Nava JI, Saldaña-Cruz AM, Gonzalez-Ponce F, Contreras-Haro B, Ramirez-Villafaña M, Perez-Guerrero EE, Alcaraz-Lopez MF, Gomez-Ramirez EE, Ponce-Guarneros JM, Rodriguez-Jimenez NA, Totsuka-Sutto SE, Rocha-Muñoz AD, Muñoz-Miranda LA, Gonzalez-Lopez L, Nava-Valdivia CA.   +15 more
europepmc   +1 more source

The Tangled Web of Integrating Health and Social Services in Canada. [PDF]

Healthc Policy, 2023
Sutherland JM.
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Contrast and addition: comparatives and superlatives

, 2018
El vídeo describe el contenido del curso de Contrast and addition: comparatives and superlatives, además de describir las unidades didácticas a ...
Pérez Palma, Marco Meza
core  

Comparing Multilingual Comparable Articles Based On Opinions.

, 2013
Multilingual sentiment analysis attracts increased attention as the massive growth of multilingual web contents. This conducts to study opinions across different languages by comparing the underlying messages written by different people having different opinions. In this paper, we propose Sentiment based Comparability Measures (SCM) to compare opinions
Saad M., Langlois D., Smaili K.
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

How do I publish the name of a new species of algae? A basic guide. [PDF]

J Phycol
Guiry MD.
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Mental states via possessive predication: the grammar of possessive experiencer complex predicates in Persian. [PDF]

Nat Lang Semant
Smith RW.
europepmc   +1 more source