THE EVOLUTION OF ROMANIA’S GROSS DOMESTIC PRODUCT IN THE LAST TEN YEARS [PDF]
This paper proposes a complex analysis of the GDP’s evolution inour country. Given the position of the indicator in the context of the national economy, such analysis is much more important, knowing that the results outline the performances of all ...
Constantin ANGHELACHE
doaj
Virome comparisons in wild-diseased and healthy captive giant pandas [PDF]
Wen Zhang +20 more
openalex +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Comparison of Coupled and Uncoupled Currents during Glutamate Uptake by GLT-1 Transporters [PDF]
Dwight E. Bergles +2 more
openalex +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Comparison of primary total hip replacements performed with a direct anterior approach versus the standard lateral approach: perioperative findings [PDF]
Vincenzo Alecci +5 more
openalex +1 more source
Comparison of lumen-apposing metal stents versus double-pigtail plastic stents for infected necrotising pancreatitis [PDF]
Lotte Boxhoorn +39 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source

