Results 191 to 200 of about 18,196,531 (326)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Sex-Specific transcriptomic changes in adipose tissue following adult-onset disruption of growth hormone receptor. [PDF]

Pituitary
Duran-Ortiz S, Young JA, List EO, Basu R, Walsh C, Gotte EA, Berryman DE, Kopchick JJ.   +7 more
europepmc   +1 more source

Comparison of single‑nucleus and single‑cell transcriptomes in hepatocellular carcinoma tissue

, 2022
Fei Wen, Xiaojie Tang, Xu Lin, Haixia Qu
openalex   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

The effect of 2′-fucosyllactose on simulated infant gut microbiome and metabolites; a pilot study in comparison to GOS and lactose

, 2019
Krista Salli, Heli Anglenius, Johanna Hirvonen, Ashley A. Hibberd, Ilmari Ahonen, Markku Saarinen, Kirsti Tiihonen, Johanna Maukonen, Arthur C. Ouwehand   +8 more
openalex   +1 more source

Production, characterization, and bioactivity of novel camel milk-based infant formula in comparison to bovine and commercial sources

, 2021
Priti Mudgil, Waqas N. Baba, Meera Ahmed Khalfan Alneyadi, Ali Ali Redha, Sajid Maqsood   +4 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Influence of sevoflurane combined with propofol anesthesia on the anesthesia effect and adverse reactions in children with acute appendicitis. [PDF]

Open Med (Wars)
Zhang P, Zhang J, Chen F.
europepmc   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Improving perinatal mood and anxiety disorders through integrated infant mental health care in obstetrics: evidence from a program evaluation study. [PDF]

BMC Pregnancy Childbirth
Jester JM, Hoffman CM, Issa M, Riggs JL, O'Neill H, Duprey M, Rosenblum K, Erickson NL, Bengel C, Fisk C, Muzik M.   +10 more
europepmc   +1 more source