Glomerular Filtration Rate, Albuminuria, and Reported Kidney Disease in Comparison: Results From the German National Cohort (NAKO). [PDF]
Sekula P +37 more
europepmc +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
A COMPARISON OF THE RESULTS OF THE PREOPERATIVE
Hiromasa FUJITA +10 more
openaire +3 more sources
Evaluation of a new design solution for the visualisation of a risk-adjusted hospital performance comparison: results of an end user-centred mixed methods study. [PDF]
Bernet NS +7 more
europepmc +1 more source
openThis study investigates the role of social media social comparison in self-esteem and emotion regulation on Italian high school students, aged from 14 to 19 who participated in two online sessions, completing anonymous questionnaires.
RICCO, ROBERTA
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Evaluation of Emerging Antimicrobials Resistance in Nosocomial Infections Caused by E. coli: The Comparison Results of Observed Cases and Compartmental Model. [PDF]
Eshrati B +9 more
europepmc +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Methods for Indirect Treatment Comparison: Results from a Systematic Literature Review. [PDF]
Macabeo B +5 more
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source

