Results 111 to 120 of about 3,221,559 (262)

Comparisons of real output in manufacturing [PDF]

open access: yes
This study is concerned with the conceptual and measurement problems which arise in comparisons of levels of per capita output and productivity in different countries.
van Ark, Bart, Maddison, Angus
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Improving International Comparisons of Real Output: The ICP 2005 Benchmark and its Implications for China [PDF]

open access: yes
The latest round of the International Comparisons Program (ICP 2005) compares the purchasing power of currencies and real output of 146 countries. Using price quote data from nine countries in the Asia-Pacific region, we consider ways of improving the ...
Iqbal Syed, Robert J. Hill
core  

Nonparametric Predictive Inference for Multiple Comparisons [PDF]

open access: yes, 2010
This thesis presents Nonparametric Predictive Inference (NPI) for several multiple comparisons problems. We introduce NPI for comparison of multiple groups of data including right-censored observations.
Maturi, T.A., MATURI, TAHANI
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Progressivity comparisons [PDF]

open access: yes
Analysts should correct for distributional differences before undertaking local progressivity comparisons between income tax or tax and benefit schedules.
Peter J. Lambert, Valentino Dardoni
core  

Message-passing computing with Java: performance evaluation and comparisons

open access: yes, 2001
The development of Java has seen increasing attention as the most popular platform for distributed computing. However, despite Java's advantages in the area of portability and rapid prototyping, its efficiency is unavoidably compromised through its ...
Getov, Vladimir   +3 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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